PDE3A Antikörper

Produktnummer ABIN2747088

Produktdetails anti-PDE3A Antikörper

Target: PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

Reaktivität: Human, Ratte, Maus, Affe, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA

Aufreinigung: Affinity Purified

Immunogen: Synthetic peptide selective only for PDE3A variants

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.72 μg/μL

Referenzen für anti-PDE3A Antikörper (ABIN2747088)

Fields, Koschinski, Zaccolo: "Sustained exposure to catecholamines affects cAMP/PKA compartmentalised signalling in adult rat ventricular myocytes." in: Cellular signalling, Vol. 28, Issue 7, pp. 725-32, (2017) (PubMed).

Yang, Kirton, MacDougall, Boyle, Deuchars, Frater, Ponnambalam, Hardy, White, Calaghan, Peers, Steele: "The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway." in: Science signaling, Vol. 8, Issue 398, pp. ra101, (2016) (PubMed).

Rajagopal, Nalli, Kumar, Bhattacharya, Hu, Mahavadi, Grider, Murthy: "Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation." in: The Journal of pharmacology and experimental therapeutics, Vol. 352, Issue 3, pp. 509-18, (2015) (PubMed).

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." in: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Mahavadi, Nalli, Kumar, Hu, Kuemmerle, Grider, Murthy: "Cytokine-induced iNOS and ERK1/2 inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle." in: American journal of physiology. Cell physiology, Vol. 307, Issue 4, pp. C402-11, (2014) (PubMed).

Vang, Housley, Dong, Basole, Ben-Sasson, Kream, Epstein, Clark, Brocke: "Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac." in: The Biochemical journal, Vol. 456, Issue 3, pp. 463-73, (2013) (PubMed).

Ückert, Waldkirch, Sonnenberg, Sandner, Kuczyk, Hedlund: "Expression and distribution of phosphodiesterase isoenzymes in the human seminal vesicles." in: The journal of sexual medicine, Vol. 8, Issue 11, pp. 3058-65, (2012) (PubMed).

Nishioka, Nishida, Ariyoshi, Jian, Saiki, Hirano, Nakaya, Sato, Kita, Iwamoto, Hirano, Inoue, Kurose: "Cilostazol suppresses angiotensin II-induced vasoconstriction via protein kinase A-mediated phosphorylation of the transient receptor potential canonical 6 channel." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 31, Issue 10, pp. 2278-86, (2011) (PubMed).

Dov, Abramovitch, Warwar, Nesher: "Diminished phosphodiesterase-8B potentiates biphasic insulin response to glucose." in: Endocrinology, Vol. 149, Issue 2, pp. 741-8, (2008) (PubMed).

Dony, Lai, Dumitrascu, Pullamsetti, Savai, Ghofrani, Weissmann, Schudt, Flockerzi, Seeger, Grimminger, Schermuly: "Partial reversal of experimental pulmonary hypertension by phosphodiesterase-3/4 inhibition." in: The European respiratory journal, Vol. 31, Issue 3, pp. 599-610, (2008) (PubMed).

Uckert, Oelke, Stief, Andersson, Jonas, Hedlund: "Immunohistochemical distribution of cAMP- and cGMP-phosphodiesterase (PDE) isoenzymes in the human prostate." in: European urology, Vol. 49, Issue 4, pp. 740-5, (2007) (PubMed).

Albrecht, Uckert, Oelke, Andersson, Jonas, Tröger, Hedlund: "Immunohistochemical distribution of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human vagina: a potential forensic value?" in: Journal of forensic and legal medicine, Vol. 14, Issue 5, pp. 270-4, (2007) (PubMed).

Ückert, Oelke, Albrecht, Stief, Jonas, Hedlund: "Immunohistochemical description of cyclic nucleotide phosphodiesterase (PDE) isoenzymes in the human labia minora." in: The journal of sexual medicine, Vol. 4, Issue 3, pp. 602-608, (2007) (PubMed).

Oelke, Hedlund, Albrecht, Ellinghaus, Stief, Jonas, Andersson, Uckert: "Expression of cAMP and cGMP-phosphodiesterase isoenzymes 3, 4, and 5 in the human clitoris: immunohistochemical and molecular biology study." in: Urology, Vol. 67, Issue 5, pp. 1111-6, (2006) (PubMed).

Uckert, Hedlund, Waldkirch, Sohn, Jonas, Andersson, Stief: "Interactions between cGMP- and cAMP-pathways are involved in the regulation of penile smooth muscle tone." in: World journal of urology, Vol. 22, Issue 4, pp. 261-6, (2005) (PubMed).

Netherton, Maurice: "Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migration: implications in angiogenesis." in: Molecular pharmacology, Vol. 67, Issue 1, pp. 263-72, (2005) (PubMed).

Uckert, Oelke, Waldkirch, Stief, Albrecht, Tröger, Jonas, Andersson, Hedlund: "Cyclic adenosine monophosphate and cyclic guanosine monophosphate-phosphodiesterase isoenzymes in human vagina: relation to nitric oxide synthase isoforms and vasoactive intestinal polypeptide-containing nerves." in: Urology, Vol. 65, Issue 3, pp. 604-10, (2005) (PubMed).

Mongillo, McSorley, Evellin, Sood, Lissandron, Terrin, Huston, Hannawacker, Lohse, Pozzan, Houslay, Zaccolo: "Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases." in: Circulation research, Vol. 95, Issue 1, pp. 67-75, (2004) (PubMed).

Details zu PDE3A

Target: PDE3A (phosphodiesterase 3A, cGMP-Inhibited (PDE3A))

Andere Bezeichnung: PDE3A (PDE3A Produkte)

Synonyme: PDE3A antikoerper, Pde3a antikoerper, si:dkey-48h7.2 antikoerper, A930022O17Rik antikoerper, C87899 antikoerper, RNPDE3A antikoerper, CGI-PDE antikoerper, CGI-PDE A antikoerper, CGI-PDE-A antikoerper, phosphodiesterase 3A antikoerper, phosphodiesterase 3A, cGMP-inhibited antikoerper, cGMP-inhibited 3',5'-cyclic phosphodiesterase A antikoerper, phosphodiesterase 3A, cGMP inhibited antikoerper, PDE3A antikoerper, Pde3a antikoerper, LOC100540515 antikoerper, pde3a antikoerper

NCBI Accession: NP_000912

UniProt: Q14432

Pathways: cAMP Metabolic Process