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CD2 Antikörper

CD2 Reaktivität: Human FACS, Func Wirt: Maus Monoclonal TS1-8 unconjugated
Produktnummer ABIN2749021
  • Target Alle CD2 Antikörper anzeigen
    CD2
    Reaktivität
    • 166
    • 35
    • 15
    • 13
    • 12
    • 10
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 133
    • 44
    • 23
    • 1
    Maus
    Klonalität
    • 156
    • 43
    • 2
    Monoklonal
    Konjugat
    • 83
    • 23
    • 20
    • 15
    • 9
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD2 Antikörper ist unkonjugiert
    Applikation
    • 142
    • 52
    • 51
    • 33
    • 31
    • 30
    • 20
    • 11
    • 10
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Functional Studies (Func)
    Spezifität
    The mouse monoclonal antibody TS1/8 recognizes an extracellular epitope of CD2, a 50 kDa glycoprotein present on the human peripheral blood T lymphocytes and NK cells, also expressed by all thymocytes.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Endotoxin-Niveau
    Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
    Immunogen
    Cytotoxic T lymphocytes
    Klon
    TS1-8
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product CD2 Primärantikörper
  • Applikationshinweise
    Functional application: Blocking.
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Zhang, Dai, Li, Zhuang: "Tracking proliferative history in lymphocyte development with cre-mediated sister chromatid recombination." in: PLoS genetics, Vol. 9, Issue 10, pp. e1003887, (2013) (PubMed).

  • Target
    CD2
    Andere Bezeichnung
    CD2 (CD2 Produkte)
    Synonyme
    CD2 antikoerper, LFA-2 antikoerper, Ly-37 antikoerper, Ly37 antikoerper, SRBC antikoerper, T11 antikoerper, CD2R antikoerper, LFA2 antikoerper, OX-34 antikoerper, OX34 antikoerper, CD2 molecule antikoerper, CD2 antigen antikoerper, Cd2 molecule antikoerper, CD2 antikoerper, Cd2 antikoerper
    Hintergrund
    CD2 Molecule,CD2 belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.,T11, LFA-2, SRBC
    Gen-ID
    914
    UniProt
    P06729
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