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SIGLEC7 Antikörper

SIGLEC7 Reaktivität: Human FACS Wirt: Maus Monoclonal 6-434 unconjugated
Produktnummer ABIN2749061
  • Target Alle SIGLEC7 Antikörper anzeigen
    SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
    Reaktivität
    • 86
    • 11
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 63
    • 23
    Maus
    Klonalität
    • 63
    • 22
    • 1
    Monoklonal
    Konjugat
    • 37
    • 12
    • 10
    • 9
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SIGLEC7 Antikörper ist unkonjugiert
    Applikation
    • 64
    • 45
    • 40
    • 16
    • 9
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody 6-434 recognizes an extracellular epitope of CD328 (Siglec-7), a 75 kDa transmembrane glycoprotein expressed mainly on NK cells, dendritic cells and monocytes.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    human dendritic cells
    Klon
    6-434
    Isotyp
    IgG1
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  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
    Andere Bezeichnung
    CD328 / Siglec-7 (SIGLEC7 Produkte)
    Synonyme
    SIGLEC7 antikoerper, AIRM1 antikoerper, CD328 antikoerper, CDw328 antikoerper, D-siglec antikoerper, QA79 antikoerper, SIGLEC-7 antikoerper, SIGLEC19P antikoerper, SIGLECP2 antikoerper, p75 antikoerper, p75/AIRM1 antikoerper, sialic acid-binding Ig-like lectin 7 antikoerper, sialic acid binding Ig like lectin 7 antikoerper, LOC468976 antikoerper, SIGLEC7 antikoerper
    Hintergrund
    Sialic acid binding Ig like lectin 7,CD328, also known as Siglec-7 or p75/AIRM1, is a 75 kDa type I transmembrane glycoprotein of sialic acid-binding immunoglobulin-like lectin (Siglec) family. CD328 binds to sialylated glycans with alpha2,6 sialyl and alpha2,8 disyalyl residues and mediates sialic acid-dependent cell-cell binding. As it contains in its intracellular part the immunoreceptor tyrosine-based inhibitory motif (ITIM), it serves as an inhibitory receptor, e.g. of NK cells.,SIGLEC7, p75/AIRM1, D-siglec
    Gen-ID
    27036
    UniProt
    Q9Y286
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