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PCLO Antikörper

PCLO Reaktivität: Human WB, FACS Wirt: Maus Monoclonal PCLO-01 unconjugated
Produktnummer ABIN2749094
  • Target Alle PCLO Antikörper anzeigen
    PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))
    Reaktivität
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 6
    • 1
    Maus
    Klonalität
    • 4
    • 3
    Monoklonal
    Konjugat
    • 5
    • 2
    Dieser PCLO Antikörper ist unkonjugiert
    Applikation
    • 6
    • 3
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody PCLO-01 recognizes PCLO (Piccolo), a more than 400 kDa multidomain protein expressed mainly in the presynaptic cytoplasmatic matrix of the neurons.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    Human recombinant PCLO protein
    Klon
    PCLO-01
    Isotyp
    IgG1
    Top Product
    Discover our top product PCLO Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-5 μg/mL, intracellular staining.
    Western blotting: A small splice variant of PCLO can be analyzed by Western blotting, however, the whole protein is too large (over 400 kDa) to be successfully processed by SDS PAAGE.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    PCLO (Piccolo (Presynaptic Cytomatrix Protein) (PCLO))
    Andere Bezeichnung
    PCLO (PCLO Produkte)
    Synonyme
    pclo antikoerper, wu:fj53e09 antikoerper, Acz antikoerper, Pico antikoerper, mKIAA0559 antikoerper, aczonin antikoerper, PCLO antikoerper, ACZ antikoerper, piccolo presynaptic cytomatrix protein antikoerper, piccolo presynaptic cytomatrix protein a antikoerper, piccolo (presynaptic cytomatrix protein) antikoerper, PCLO antikoerper, pcloa antikoerper, Pclo antikoerper, LOC768552 antikoerper
    Hintergrund
    Piccolo presynaptic cytomatrix protein,PCLO (piccolo, also known as aczonin) is a large (more than 400 kDa) multidomain protein of the presynaptic cytomatrix in neurons, that is present in all vertebrate synapses, but is absent from invertebrates. It contains zinc finger and coiled-coil sequences, as well as N-terminal glutamine-rich sequence, and C-terminal PDZ domain followed by two C2 domains (C2A and C2B). In vitro binding and transfection experiments suggested that PCLO binds to multiple proteins including profilin and L-type calcium channels. It is involved in neurotransmitter release and insulin secretion.,ACZ, PCH3, piccolo, aczonin
    Gen-ID
    27445
    UniProt
    Q9Y6V0
    Pathways
    Hormone Transport, Synaptic Vesicle Exocytosis
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