The mouse monoclonal antibody OPAL1-01 recognizes an intracellular epitope of OPAL1 (outcome predictor in acute leukemia 1), a transmembrane adaptor protein expressed mainly by megacaryocytes and platelets.
Kreuzreaktivität (Details)
Human
Aufreinigung
Purified by protein-A affinity chromatography.
Reinheit
> 95 % (by SDS-PAGE)
Immunogen
Recombinant fragment of human OPAL1 (amino acids 152-342)
D19Wsu162e antikoerper, Opal1 antikoerper, C10orf26 antikoerper, OPA1L antikoerper, OPAL1 antikoerper, RGD1305793 antikoerper, WW domain binding protein 1 like antikoerper, WW domain binding protein 1-like antikoerper, Wbp1l antikoerper, WBP1L antikoerper
Hintergrund
WW domain binding protein 1 like,OPAL1 (outcome predictor in acute leukemia 1) is an almost uncharacterized transmembrane adaptor protein expressed mainly by megacaryocytes and platelets. Its expression is enhanced on TEL/AML leukemic cells. The function of OPAL1 is unknown, although the presence of a cytochrome c-like heme-binding site and a transmembrane domain suggested OPAL1 may be involved in the mitochondrial electron transport chain. Its originally reported prognostic impact appears to be treatment dependent.,WBP1L