Cadherin 5 Antikörper
(2 Referenzen)-
- Target Alle Cadherin 5 (CDH5) Antikörper anzeigen
- Cadherin 5 (CDH5)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Cadherin 5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- The mouse monoclonal antibody 55-7H1 recognizes a calcium-independent extracellular epitope on CD144 (VE-cadherin, cadherin 5), an adhesion molecule expressed on endothelial cells.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- Human endothelial cells
- Klon
- 55-7H1
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CDH5 Primärantikörper
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anti-Cadherin 5 (CDH5) (AA 601-700) antibody
CDH5 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, ICC, IHC (p), IHC (fro), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 68-307) antibodyCDH5 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 29-223) antibodyCDH5 Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 3D5C7 unconjugated
anti-Cadherin 5 (CDH5) (AA 29-223) antibodyCDH5 Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 3D5C7 unconjugated
anti-Cadherin 5 (CDH5) (AA 650-750) antibodyCDH5 Reaktivität: Human WB, IHC, IP, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (C-Term) antibodyCDH5 Reaktivität: Human, Maus WB, IHC, ELISA, ICC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 26-194) antibodyCDH5 Reaktivität: Human WB, IHC, IP, IF Wirt: Maus Monoclonal 75-Cadherin unconjugated
anti-Cadherin 5 (CDH5) (AA 766-784) antibodyCDH5 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 59-382) antibodyCDH5 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cadherin 5 (CDH5) (AA 251-320) antibodyCDH5 Reaktivität: Human, Maus FACS, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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: "Establishment of a human in vitro model of the outer blood-retinal barrier." in: Journal of anatomy, Vol. 211, Issue 6, pp. 707-16, (2007) (PubMed).
: "Sphingosine kinase-1 enhances endothelial cell survival through a PECAM-1-dependent activation of PI-3K/Akt and regulation of Bcl-2 family members." in: Blood, Vol. 105, Issue 8, pp. 3169-77, (2005) (PubMed).
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: "Establishment of a human in vitro model of the outer blood-retinal barrier." in: Journal of anatomy, Vol. 211, Issue 6, pp. 707-16, (2007) (PubMed).
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- Target
- Cadherin 5 (CDH5)
- Andere Bezeichnung
- CD144 (CDH5 Produkte)
- Hintergrund
- Cadherin 5,CD144 / VE-cadherin (cadherin 5) is the major cadherin that is present at endothelial junctions. It is also strictly endothelial specific. Under vascular permeability increasing conditions (and also in capillaries and veins) CD144 is being phosphorylated, which promotes its rapid and reversible internalization. On the contrary, binding of p120 catenin (delta1 catenin) maintains CD144 localization at the plasma membrane, which stabilizes the junction and reduces vascular permeability.,Cadherin 5, CDH5, 7B4, VE-cadherin
- Gen-ID
- 1003
- UniProt
- P33151
- Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2
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