DLL4 Antikörper
(3 Referenzen)-
- Target Alle DLL4 Antikörper anzeigen
- DLL4 (delta-Like 4 (DLL4))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser DLL4 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Functional Studies (Func)
- Spezifität
- The mouse monoclonal antibody MHD4-46 recognizes the extracellular domain of DLL4 (Delta-like ligand 4), a type I transmembrane protein which plays an important role in vascular development.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Endotoxin-Niveau
- Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
- Immunogen
- recombinant soluble human DLL4
- Klon
- MHD4-46
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product DLL4 Primärantikörper
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anti-delta-Like 4 (DLL4) (AA 313-439) antibody
DLL4 Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 4A11F8 unconjugated
anti-delta-Like 4 (DLL4) antibodyDLL4 Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 4A11 unconjugated
anti-delta-Like 4 (DLL4) (AA 215-331) antibodyDLL4 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-delta-Like 4 (DLL4) (Internal Region) antibodyDLL4 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-delta-Like 4 (DLL4) (AA 625-652), (C-Term) antibodyDLL4 Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB23696 unconjugated
anti-delta-Like 4 (DLL4) antibodyDLL4 Reaktivität: Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
anti-delta-Like 4 (DLL4) antibodyDLL4 Reaktivität: Human WB, EIA Wirt: Maus Monoclonal 4A11F8-4A11G2 unconjugated
anti-delta-Like 4 (DLL4) antibodyDLL4 Reaktivität: Human FACS Wirt: Maus Monoclonal MHD4-46 unconjugated
anti-delta-Like 4 (DLL4) (AA 44-345) antibodyDLL4 Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-delta-Like 4 (DLL4) (AA 123-221) antibodyDLL4 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
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- Applikationshinweise
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Functional application: Blocking.
Flow cytometry: Recommended dilution: 1-4 μg/mL - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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: "Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes." in: Arthritis research & therapy, Vol. 14, Issue 2, pp. R45, (2012) (PubMed).
: "Blockade of delta-like ligand 4 signaling inhibits both growth and angiogenesis of pancreatic cancer." in: Pancreas, Vol. 39, Issue 6, pp. 897-903, (2010) (PubMed).
: "Role of ephrinB2 in nonproductive angiogenesis induced by Delta-like 4 blockade." in: Blood, Vol. 113, Issue 15, pp. 3631-9, (2009) (PubMed).
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: "Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes." in: Arthritis research & therapy, Vol. 14, Issue 2, pp. R45, (2012) (PubMed).
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- Target
- DLL4 (delta-Like 4 (DLL4))
- Andere Bezeichnung
- DLL4 (DLL4 Produkte)
- Synonyme
- hdelta2 antikoerper, Delta4 antikoerper, si:ch211-244p18.5 antikoerper, zgc:136596 antikoerper, delta like canonical Notch ligand 4 antikoerper, delta-like 4 (Drosophila) antikoerper, DLL4 antikoerper, Dll4 antikoerper, dll4 antikoerper
- Hintergrund
- Delta like canonical Notch ligand 4,DLL4 (Delta-like 4) is one of five ligands of Notch receptors. It interacts with Notch1 and Notch4. DLL4 is up-regulated at sites of physiologic and pathologic angiogenesis, whereas its expression is low in most adult normal tissues. It is also highly expressed in human clear-cell renal carcinomas, bladder cancers, and breast cancers. Blocking the DLL4-Notch interaction seems to be a promissing therapeutic approach.,Delta like ligand 4, AOS6, canonical Notch ligand 4
- Gen-ID
- 54567
- UniProt
- Q9NR61
- Pathways
- Notch Signalweg
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