CYP46A1 Antikörper (C-Term)
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- Target Alle CYP46A1 Antikörper anzeigen
- CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Meerschweinchen, Ziege
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYP46A1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- YVMGRMDTYF EDPLTFNPDR FGPGAPKPRF TYFPFSLGHR SCIGQQFAQM
- Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CYP46A1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CYP46A1
- Top Product
- Discover our top product CYP46A1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 500 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))
- Andere Bezeichnung
- CYP46A1 (CYP46A1 Produkte)
- Synonyme
- CP46 antikoerper, CYP46 antikoerper, CYP46A1 antikoerper, zgc:109896 antikoerper, MGC147389 antikoerper, Cyp46 antikoerper, cytochrome P450 family 46 subfamily A member 1 antikoerper, cytochrome P450 family 46 subfamily A member 1 L homeolog antikoerper, cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 antikoerper, cytochrome P450, family 46 antikoerper, cytochrome P450 46A1 antikoerper, cytochrome P450, family 46, subfamily a, polypeptide 1 antikoerper, cholesterol 24-hydroxylase antikoerper, cytochrome P450, family 46, subfamily A, polypeptide 1 antikoerper, CYP46A1 antikoerper, cyp46a1.L antikoerper, cyp46a1.1 antikoerper, cyp46a1 antikoerper, PTRG_08343 antikoerper, PTRG_09667 antikoerper, Cyp46a1 antikoerper, Sgly_1093 antikoerper
- Hintergrund
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CYP46A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids.This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CP46, CYP46
Protein Size: 500 - Molekulargewicht
- 57 kDa
- Gen-ID
- 10858
- NCBI Accession
- NM_006668, NP_006659
- UniProt
- Q9Y6A2
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