NSDHL Antikörper (Middle Region)

Produktnummer ABIN2773893

Produktdetails anti-NSDHL Antikörper

Target: NSDHL (NAD(P) Dependent Steroid Dehydrogenase-Like (NSDHL))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NSDHL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RAVLGANDPE KNFLTTAIRP HGIFGPRDPQ LVPILIEAAR NGKMKFVIGN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NSDHL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NSDHL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 373 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NSDHL

Target: NSDHL (NAD(P) Dependent Steroid Dehydrogenase-Like (NSDHL))

Andere Bezeichnung: NSDHL (NSDHL Produkte)

Synonyme: zgc:112474 antikoerper, H105E3 antikoerper, SDR31E1 antikoerper, XAP104 antikoerper, AI747449 antikoerper, Bpa antikoerper, Str antikoerper, NAD(P) dependent steroid dehydrogenase-like antikoerper, NAD(P) dependent steroid dehydrogenase-like L homeolog antikoerper, NSDHL antikoerper, nsdhl antikoerper, nsdhl.L antikoerper, Nsdhl antikoerper

Hintergrund: NSDHL is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in NSDHL gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males.The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene.
Alias Symbols: H105E3, XAP104, SDR31E1
Protein Interaction Partner: UBC, FUS, SUMO3,
Protein Size: 373

Molekulargewicht: 42 kDa

Gen-ID: 50814

NCBI Accession: NM_015922, NP_057006

UniProt: Q15738