ST14 Antikörper (C-Term)

Produktnummer ABIN2773910

Produktdetails anti-ST14 Antikörper

Target: ST14 (Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Schwein, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ST14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SHVFPAGKAI WVTGWGHTQY GGTGALILQK GEIRVINQTT CENLLPQQIT

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ST14. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ST14

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 855 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ST14 Antikörper (ABIN2773910)

Landova Sulcova, Zahradnicek, Dumkova, Dosedelova, Krivanek, Hampl, Kavkova, Zikmund, Gregorovicova, Sedmera, Kaiser, Tucker, Buchtova: "Developmental mechanisms driving complex tooth shape in reptiles." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 249, Issue 4, pp. 441-464, (2020) (PubMed).

Details zu ST14

Target: ST14 (Suppression of Tumorigenicity 14 (Colon Carcinoma) (ST14))

Andere Bezeichnung: ST14 (ST14 Produkte)

Synonyme: HAI antikoerper, MT-SP1 antikoerper, MTSP1 antikoerper, PRSS14 antikoerper, SNC19 antikoerper, TADG15 antikoerper, TMPRSS14 antikoerper, XMT-SP1 antikoerper, hai antikoerper, mt-sp1 antikoerper, mtsp1 antikoerper, prss14 antikoerper, snc19 antikoerper, st14 antikoerper, st14a antikoerper, tadg15 antikoerper, tmprss1 antikoerper, Epithin antikoerper, Prss14 antikoerper, Tmprss14 antikoerper, mCAP3 antikoerper, matriptase antikoerper, suppression of tumorigenicity 14 antikoerper, suppression of tumorigenicity 14 L homeolog antikoerper, suppression of tumorigenicity 14 (colon carcinoma) antikoerper, ST14 antikoerper, st14.L antikoerper, St14 antikoerper

Hintergrund: ST14 is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.
Alias Symbols: HAI, MT-SP1, MTSP-1, MTSP1, PRSS14, SNC19, TADG-15, TADG15, TMPRSS14
Protein Interaction Partner: UBC, RGS16, PDGFC, CDCP1, SPINT1, F2RL1, PLAU, HGF,
Protein Size: 855

Molekulargewicht: 95 kDa

Gen-ID: 6768

NCBI Accession: NM_021978

UniProt: Q9Y5Y6