Peroxiredoxin 1 Antikörper (N-Term)

Produktnummer ABIN2773920

Produktdetails anti-Peroxiredoxin 1 Antikörper

Target: Peroxiredoxin 1 (PRDX1)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Peroxiredoxin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SSGNAKIGHP APNFKATAVM PDGQFKDISL SDYKGKYVVF FFYPLDFTFV

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against PRDX1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRDX1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 199 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Peroxiredoxin 1

Target: Peroxiredoxin 1 (PRDX1)

Andere Bezeichnung: PRDX1 (PRDX1 Produkte)

Hintergrund: PRDX1 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. It may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: MSP23, NKEFA, PAG, PAGA, PAGB, PRX1, TDPX2, PRXI
Protein Interaction Partner: FUS, UBC, MDM2, RPA3, RPA2, RPA1, SUZ12, CACYBP, HECTD1, PRDX2, PRKDC, PPP2R5D, METTL1, PARK2, YWHAQ, VHL, EGFR, CDK2, RAD52, MPG, US3, SH2D1B, LUC7L, HCVgp1, PRDX4, IQCB1, BTRC, UBL4A, VCAM1, SMARCD1, FN1, DAB2, ADH5, ABL1, MYD88, MYC, ITGA4, TIPIN, EIF4
Protein Size: 199

Molekulargewicht: 22 kDa

Gen-ID: 5052

NCBI Accession: NM_002574, NP_002565

UniProt: Q06830

Pathways: p53 Signalweg, EGFR Signaling Pathway, CXCR4-mediated Signaling Events