PRTFDC1 Antikörper (Middle Region)

Produktnummer ABIN2773930

Produktdetails anti-PRTFDC1 Antikörper

Target: PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Schwein, Pferd, Kaninchen, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRTFDC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MKALLSNIEK YKPNMIKVAS LLVKRTSRSD GFRPDYAGFE IPNLFVVGYA

Homologie: Dog: 92%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 77%, Rat: 92%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against PRTFDC1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PRTFDC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 225 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PRTFDC1 Antikörper (ABIN2773930)

Suzuki, Imoto, Pimkhaokham, Nakagawa, Kamata, Kozaki, Amagasa, Inazawa: "PRTFDC1, a possible tumor-suppressor gene, is frequently silenced in oral squamous-cell carcinomas by aberrant promoter hypermethylation." in: Oncogene, Vol. 26, Issue 57, pp. 7921-32, (2007) (PubMed).

Details zu PRTFDC1

Target: PRTFDC1 (phosphoribosyl Transferase Domain Containing 1 (PRTFDC1))

Andere Bezeichnung: PRTFDC1 (PRTFDC1 Produkte)

Synonyme: HHGP antikoerper, HPRT antikoerper, hprt1 antikoerper, hprt1l antikoerper, zgc:55561 antikoerper, zgc:86771 antikoerper, MGC80959 antikoerper, OTTMUSG00000011667 antikoerper, Prtfdc1 antikoerper, phosphoribosyl transferase domain containing 1 antikoerper, phosphoribosyl transferase domain containing 1 L homeolog antikoerper, phosphoribosyltransferase domain containing 1 pseudogene antikoerper, PRTFDC1 antikoerper, prtfdc1 antikoerper, Prtfdc1 antikoerper, prtfdc1.L antikoerper, Gm13377 antikoerper

Hintergrund: PRTFDC1 belongs to the purine/pyrimidine phosphoribosyltransferase family. Epigenetic silencing of PRTFDC1 by hypermethylation of the CpG islands leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis.
Alias Symbols: FLJ11888, HHGP
Protein Interaction Partner: LGALS9B, EEF2KMT, MCMBP, GNPDA1, EPM2AIP1, TCL1A, HPRT1, UBC, RTN3, FLAD1, NIF3L1, DTNB, STAT5A, EWSR1,
Protein Size: 225

Molekulargewicht: 26 kDa

Gen-ID: 56952

NCBI Accession: NM_020200, NP_064585

UniProt: Q9NRG1

Pathways: Ribonucleoside Biosynthetic Process