CDR2 Antikörper (N-Term)

Produktnummer ABIN2773981

Produktdetails anti-CDR2 Antikörper

Target: CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDR2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Sequenz: MLAENLVEEF EMKEDEPWYD HQDLQQDLQL AAELGKTLLD RNTELEDSVQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against CDR2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CDR2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 454 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CDR2

Target: CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))

Andere Bezeichnung: CDR2 (CDR2 Produkte)

Synonyme: CDR62 antikoerper, Yo antikoerper, cdr2 antikoerper, MGC69206 antikoerper, CDR2 antikoerper, AA617262 antikoerper, RGD1310578 antikoerper, cerebellar degeneration related protein 2 antikoerper, cerebellar degeneration related protein 2 L homeolog antikoerper, cerebellar degeneration-related 2 antikoerper, cerebellar degeneration-related protein 2 antikoerper, cerebellar degeneration related protein 2 like antikoerper, CDR2 antikoerper, cdr2 antikoerper, cdr2.L antikoerper, Cdr2 antikoerper, CDR2L antikoerper, LOC101060399 antikoerper

Hintergrund: Cdr2 normally sequesters c-Myc in the neuronal cytoplasm, thereby down-regulating c-Myc activity, and suggest a mechanism whereby inhibition of cdr2 function by autoantibodies in PCD may contribute to Purkinje neuronal.
Alias Symbols: CDR62, Yo
Protein Interaction Partner: SMARCE1, CEP57L1, KANSL1, CCDC153, C4orf46, TXLNA, ALS2CR11, C1orf216, HAUS1, ANKRD36BP1, TCHP, FAM161A, ENKD1, FAM110A, LENG1, SCNM1, SH2D4A, LIN37, RCOR3, TBC1D22B, WDYHV1, CCHCR1, AMOTL2, FZR1, RSPH14, CHIC2, MRPL28, TMCC2, HDAC4, EIF4E2, TTR, COX5B, T
Protein Size: 454

Molekulargewicht: 52 kDa

Gen-ID: 1039

NCBI Accession: NM_001802, NP_001793

UniProt: Q01850