MYCNOS Antikörper (N-Term)

Produktnummer ABIN2773988

Produktdetails anti-MYCNOS Antikörper

Target: MYCNOS (MYCN Opposite Strand/antisense RNA (MYCNOS))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYCNOS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: WGGETDASNP APALTACCAA EREANVEQGL AGRLLLCNYE RRLVRRCKIA

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MYCNOS. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 109 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MYCNOS

Target: MYCNOS (MYCN Opposite Strand/antisense RNA (MYCNOS))

Andere Bezeichnung: MYCNOS (MYCNOS Produkte)

Synonyme: MYCN-AS1 antikoerper, NCYM antikoerper, NYCM antikoerper, MYCN opposite strand antikoerper, MYCNOS antikoerper

Hintergrund: The N-myc oncogene has been implicated in the pathogenesis of a number of human tumors, including childhood neuroblastoma and adult small cell lung cancer. Complementary DNA clones derived from a transcription unit, N-cym, located on the opposite DNA strand to N-myc have been characterized. There is extensive overlap between the 5' ends of the two transcription units. The N-cym gene, which can encode a 109-amino acid protein, is expressed during fetal development, as well as in tumor cell lines containing amplified N-myc loci, where it is expressed at very high levels. Although other examples of overlapping, opposite-strand eukaryotic genes exist, N-myc and N-cym are unique in that they appear to be coregulated in tumor cell lines under basal growth conditions and in response to the differentiating agent retinoic acid. This coregulation suggests that their protein products may be functionally interrelated during normal development and oncogenesis.
Alias Symbols: NCYM, NYCM, MYCN-AS1
Protein Size: 109

Molekulargewicht: 12 kDa

Gen-ID: 10408

NCBI Accession: NM_006316, NP_006307

UniProt: P40205