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Cortactin Antikörper (N-Term)
CTTN
Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN2774002
Produktdetails anti-Cortactin Antikörper
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Target
Alle Cortactin (CTTN) Antikörper anzeigen
Cortactin (CTTN)
Bindungsspezifität
Alle Epitope für Cortactin Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für Cortactin Antikörper
Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
Wirt
Alle Wirte für Cortactin Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für Cortactin Antikörper
Polyklonal
Konjugat
Alle Konjugate für Cortactin Antikörper
Dieser Cortactin Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Cortactin Antikörper
Western Blotting (WB)
Sequenz
KSAVGFDYQG KTEKHESQRD YSKGFGGKYG IDKDKVDKSA VGFEYQGKTE
Homologie
Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 93%
Produktmerkmale
This is a rabbit polyclonal antibody against CTTN. It was validated on Western Blot.
Aufreinigung
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human CTTN
Top Product
Discover our top product CTTN Primärantikörper
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Anwendungsinformationen
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Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu Cortactin
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Target
Cortactin (CTTN)
Andere Bezeichnung
CTTN (CTTN Produkte )
Synonyme
EMS1 antikoerper, 1110020L01Rik antikoerper, Ems1 antikoerper, Cttnb antikoerper, CG3637 antikoerper, Dmel\CG3637 antikoerper, cortactin antikoerper, cttn antikoerper, CTTN1 antikoerper, P85.25 antikoerper, Cttn antikoerper, ems1 antikoerper, CTTN antikoerper, cortactin antikoerper, CG3637 gene product from transcript CG3637-RD antikoerper, cortactin S homeolog antikoerper, cortactin L homeolog antikoerper, src substrate cortactin antikoerper, Src substrate cortactin antikoerper, CTTN antikoerper, Cttn antikoerper, Cortactin antikoerper, cttn.S antikoerper, cttn.L antikoerper, cttn antikoerper, CpipJ_CPIJ006351 antikoerper, Bm1_57220 antikoerper, LOC100533277 antikoerper
Hintergrund
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. Alias Symbols: EMS1 Protein Interaction Partner: SPRR2A, CDC37, CTTN, UBC, NEDD8, RPA3, RPA2, RPA1, VTA1, GSPT2, ATG7, UGDH, ME1, IDE, GSPT1, GARS, CTNNA1, ATP6V1C1, APEH, STAT1, SSB, SNX2, SNX1, SHMT2, SHMT1, SARS, RDX, ACTR2, NPM1, LMNA, ACTG1, ACTR3, PAN2, ATF2, DNM2, NCF1, Mbp, ASAP1, CORO1B, SDHAF2 Protein Size: 634
Molekulargewicht
69 kDa
Gen-ID
2017
NCBI Accession
NM_138565 , NP_612632
Pathways
MAPK Signalweg
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