HUS1B Antikörper (N-Term)

Produktnummer ABIN2774030

Produktdetails anti-HUS1B Antikörper

Target: HUS1B (HUS1 Checkpoint Homolog B (HUS1B))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HUS1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ELFIHVSGTV ARLAKVCVLR VRPDSLCFGP AGSGGLHEAR LWCEVRQGAF

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HUS1B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HUS1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 278 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HUS1B

Target: HUS1B (HUS1 Checkpoint Homolog B (HUS1B))

Andere Bezeichnung: HUS1B (HUS1B Produkte)

Synonyme: HUS1B antikoerper, RP11-532F6.1 antikoerper, HUS1 checkpoint clamp component B antikoerper, HUS1B antikoerper, Hus1b antikoerper

Hintergrund: HUS1Bis most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. HUS1B can interact with the check point protein RAD1 but not with RAD9. Overexpression of HUS1B has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1.
Alias Symbols: MGC126746, MGC126748, RP11-532F6.1
Protein Interaction Partner: RAD9B, RAD9A, HUS1, RAD1,
Protein Size: 278

Molekulargewicht: 31 kDa

Gen-ID: 135458

NCBI Accession: NM_148959, NP_683762

UniProt: Q8NHY5