FBXO22 Antikörper (Middle Region)

Produktnummer ABIN2774089

Produktdetails anti-FBXO22 Antikörper

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Kaninchen, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CCKVGASNYL QQVVSTFSDM NIILAGGQVD NLSSLTSEKY VLCASDFVCE

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 79%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXO22. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO22

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 276 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXO22

Target: FBXO22 (F-Box Protein 22 (FBXO22))

Andere Bezeichnung: FBXO22 (FBXO22 Produkte)

Synonyme: FBXO22 antikoerper, DKFZp469L0535 antikoerper, fbxo22 antikoerper, MGC146708 antikoerper, si:busm1-132m23.3 antikoerper, FBX22 antikoerper, FISTC1 antikoerper, 0610033L19Rik antikoerper, 1600016C16Rik antikoerper, F-box protein 22 antikoerper, FBXO22 antikoerper, fbxo22 antikoerper, Fbxo22 antikoerper

Hintergrund: FBXO22 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO22 belongs to the Fbxs class. Two transcript variants encoding different isoforms exist for this gene.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Two transcript variants encoding different isoforms exist for this gene.
Alias Symbols: FBX22, FLJ13986, MGC31799, FISTC1
Protein Interaction Partner: Srr, UBC, CUL1, SKP1, NEDD8, COPS5, COPS6, RBX1,
Protein Size: 276

Molekulargewicht: 30 kDa

Gen-ID: 26263

NCBI Accession: NM_012170, NP_036302

UniProt: Q8NEZ5

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development