HSPB8 Antikörper (Middle Region)
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- Target Alle HSPB8 Antikörper anzeigen
- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Ziege, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HSPB8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- PEELMVKTKD GYVEVSGKHE EKQQEGGIVS KNFTKKIQLP AEVDPVTVFA
- Homologie
- Cow: 100%, Dog: 100%, Goat: 77%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against HSPB8. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human HSPB8
- Top Product
- Discover our top product HSPB8 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 196 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))
- Andere Bezeichnung
- HSPB8 (HSPB8 Produkte)
- Synonyme
- CMT2L antikoerper, DHMN2 antikoerper, E2IG1 antikoerper, H11 antikoerper, HMN2 antikoerper, HMN2A antikoerper, HSP22 antikoerper, MGC64408 antikoerper, hsc70 antikoerper, wu:fb01g06 antikoerper, wu:fi48b06 antikoerper, fc09c11 antikoerper, wu:fc04b04 antikoerper, wu:fc09c11 antikoerper, zgc:64202 antikoerper, AU018630 antikoerper, AW413033 antikoerper, Cryac antikoerper, D5Ucla4 antikoerper, H11K antikoerper, HSP20-like antikoerper, Hsp22 antikoerper, heat shock protein family B (small) member 8 antikoerper, heat shock protein family B (small) member 8 L homeolog antikoerper, heat shock protein 8 antikoerper, heat shock protein b8 antikoerper, HSPB8 antikoerper, hspb8.L antikoerper, hspa8 antikoerper, hspb8 antikoerper, Hspb8 antikoerper
- Hintergrund
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HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 protein is induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in the encoding HSPB8 gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Alias Symbols: CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
Protein Interaction Partner: QRICH1, HSPB7, DUSP12, BAG3, ASB4, UBC, CIAPIN1, DSTN, HSPB6, HSPB3, SNCA, CRYAB, HSPB1, HSPB8, MAPK3, PRKCA, CSNK2A1, HSPB2,
Protein Size: 196 - Molekulargewicht
- 21 kDa
- Gen-ID
- 26353
- NCBI Accession
- NM_014365, NP_055180
- UniProt
- Q9UJY1
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