ANKRD15 Antikörper (C-Term)

Produktnummer ABIN2774113

Produktdetails anti-ANKRD15 Antikörper

Target: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANKRD15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: STALSIALEA GHKDIAVLLY AHVNFAKAQS PGTPRLGRKT SPGPTHRGSF

Homologie: Cow: 100%, Dog: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KANK1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human KANK1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ANKRD15

Target: ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))

Andere Bezeichnung: KANK1 (ANKRD15 Produkte)

Synonyme: ANKRD15 antikoerper, CPSQ2 antikoerper, KANK antikoerper, A930031B09Rik antikoerper, AU015049 antikoerper, AW121052 antikoerper, Ankrd15 antikoerper, D330024H06Rik antikoerper, mKIAA0172 antikoerper, KANK1 antikoerper, ankrd15 antikoerper, kank1.2 antikoerper, DMRT1 antikoerper, KN motif and ankyrin repeat domains 1 antikoerper, KN motif and ankyrin repeat domains 1 L homeolog antikoerper, doublesex and mab-3 related transcription factor 1 antikoerper, KANK1 antikoerper, Kank1 antikoerper, kank1.L antikoerper, DMRT1 antikoerper

Hintergrund: The protein encoded by this gene belongs to the Kank family of proteins, which contain multiple ankyrin repeat domains. This family member functions in cytoskeleton formation by regulating actin polymerization. This gene is a candidate tumor suppressor for renal cell carcinoma. Mutations in this gene cause cerebral palsy spastic quadriplegic type 2, a central nervous system development disorder. A t(5,9) translocation results in fusion of the platelet-derived growth factor receptor beta gene (PDGFRB) on chromosome 5 with this gene in a myeloproliferative neoplasm featuring severe thrombocythemia. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 20.
Alias Symbols: KANK, CPSQ2, ANKRD15
Protein Size: 330

Molekulargewicht: 36 kDa

Gen-ID: 23189

NCBI Accession: NM_001256876, NP_001243805

UniProt: Q14678

Pathways: Regulation of Actin Filament Polymerization