MEMO1 Antikörper (C-Term)

Produktnummer ABIN2774163

Produktdetails anti-MEMO1 Antikörper

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Pferd, Hund, Meerschweinchen, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MEMO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KLFSKYLADP SNLFVVSSDF CHWGQRFRYS YYDESQGEIY RSIEHLDKMG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Memo1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 297 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MEMO1

Target: MEMO1 (Mediator of Cell Motility 1 (MEMO1))

Andere Bezeichnung: Memo1 (MEMO1 Produkte)

Synonyme: MGC89105 antikoerper, C2orf4 antikoerper, MEMO antikoerper, NS5ATP7 antikoerper, 0610016J10Rik antikoerper, D930048L02Rik antikoerper, RGD1309929 antikoerper, fi04d12 antikoerper, wu:fi04d12 antikoerper, zgc:55290 antikoerper, mediator of cell motility 1 antikoerper, mediator of cell motility 1 L homeolog antikoerper, MEMO1 antikoerper, memo1 antikoerper, Memo1 antikoerper, memo1.L antikoerper

Hintergrund: Memo1 may control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Memo1 is a mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
Alias Symbols: MGC116222, RGD1309929
Protein Size: 297

Molekulargewicht: 32 kDa

Gen-ID: 298787

NCBI Accession: NM_001029917, NP_001025088

UniProt: Q4QQR9