UBA1 Antikörper (N-Term)

Produktnummer ABIN2774233

Produktdetails anti-UBA1 Antikörper

Target: UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MEAGPPGSAR PAEPGPCLSG QRGADHTASA SLQSVAGTEP GRHPQAVAAV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against UBA1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UBA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1058 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-UBA1 Antikörper (ABIN2774233)

Rogers, Olivier, Meyerholz, Dupuy: "Adaptive immunity does not strongly suppress spontaneous tumors in a Sleeping Beauty model of cancer." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 8, pp. 4393-9, (2013) (PubMed).

Details zu UBA1

Target: UBA1 (Ubiquitin-Like Modifier Activating Enzyme 1 (UBA1))

Andere Bezeichnung: UBA1 (UBA1 Produkte)

Synonyme: A1S9 antikoerper, A1S9T antikoerper, A1ST antikoerper, AMCX1 antikoerper, GXP1 antikoerper, POC20 antikoerper, SMAX2 antikoerper, UBA1A antikoerper, UBE1 antikoerper, UBE1X antikoerper, DDBDRAFT_0190927 antikoerper, DDBDRAFT_0220497 antikoerper, DDB_0190927 antikoerper, DDB_0220497 antikoerper, Sbx antikoerper, Ube-1 antikoerper, Ube1x antikoerper, a1s9 antikoerper, a1s9t antikoerper, a1st antikoerper, amcx1 antikoerper, gxp1 antikoerper, poc20 antikoerper, smax2 antikoerper, uba1a antikoerper, ube1 antikoerper, ube1x antikoerper, uba1 antikoerper, uba1b antikoerper, ube antikoerper, zgc:66143 antikoerper, wu:fa01e08 antikoerper, wu:fb30f01 antikoerper, wu:fi21c11 antikoerper, wu:fj14g11 antikoerper, ubiquitin like modifier activating enzyme 1 antikoerper, ubiquitin activating enzyme E1 antikoerper, Ubiquitin-conjugating enzyme E1 antikoerper, ubiquitin-like modifier activating enzyme 1 antikoerper, ubiquitin-like modifier activating enzyme 1 S homeolog antikoerper, ubiquitin-like modifier activating enzyme 1 L homeolog antikoerper, UBA1 antikoerper, uae1 antikoerper, GL50803_4083 antikoerper, GL50803_10661 antikoerper, Uba1 antikoerper, uba1.S antikoerper, uba1.L antikoerper, uba1 antikoerper, ptr3 antikoerper

Hintergrund: UBA1 activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding an ubiquitin-E1 thioester and free AMP.The protein encoded by this gene catalyzes the first step in ubiquitin conjugation to mark cellular proteins for degradation. This gene complements an X-linked mouse temperature-sensitive defect in DNA synthesis, and thus may function in DNA repair. It is part of a gene cluster on chromosome Xp11.23. Alternatively spliced transcript variants that encode the same protein have been described.
Alias Symbols: A1S9, A1S9T, A1ST, GXP1, MGC4781, UBA1A, UBE1, UBE1X, AMCX1, POC20, SMAX2
Protein Interaction Partner: USP5, UBE2D2, UBC, FUS, ISG15, UBTD2, HUWE1, UBE2L3, UBE2D1, SUMO2, CDC34, UBE2K, UBE2W, UBE2R2, UBE2J1, UBE2T, UBE2S, UBE2C, UBE2E3, UBE2H, UBE2G2, UBE2G1, UBE2E2, UBE2E1, UBE2D3, UBE2B, UBE2A, UBI4, MDM2, TRIM25, XPNPEP1, EZR, MC1R, IPO5, FH, CTPS1, ATI
Protein Size: 1058

Molekulargewicht: 116 kDa

Gen-ID: 7317

NCBI Accession: NM_003334, NP_003325

UniProt: P22314