USP47 Antikörper (Middle Region)

Produktnummer ABIN2774253

Produktdetails anti-USP47 Antikörper

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Kaninchen, Rind (Kuh), Hund, Pferd, Ratte, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP47 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SITSSRRTKA NEGKKETWDT AEEDSGTDSE YDESGKSRGE MQYMYFKAEP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against USP47. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human USP47

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1287 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu USP47

Target: USP47 (Ubiquitin Specific Peptidase 47 (USP47))

Andere Bezeichnung: USP47 (USP47 Produkte)

Synonyme: USP47 antikoerper, zgc:165650 antikoerper, TRFP antikoerper, 4930502N04Rik antikoerper, A630020C16Rik antikoerper, ubiquitin specific peptidase 47 antikoerper, ubiquitin carboxyl-terminal hydrolase 47 antikoerper, ubiquitin specific peptidase 47 S homeolog antikoerper, Usp47 antikoerper, USP47 antikoerper, usp47 antikoerper, LOC100639726 antikoerper, usp47.S antikoerper

Hintergrund: USP47 is a putative ubiquitin-specific-processing protease that regulates cell growth and survival. USP47 probably regulates CDC25A expression at a transcriptional level. USP47 may be catalytically inactive although it seems to have kept all necessary active site residues.
Alias Symbols: DKFZp686C13257, FLJ20727, TRFP
Protein Interaction Partner: KIFC3, FBXW11, AP4M1, BTRC, UBC, WDR44, ATP6V1H, GMPPB, PDXDC1, KATNA1, HDAC6, SNCA, GRK5, SIRT7, PLA2G2A, MED9, MED29,
Protein Size: 1287

Molekulargewicht: 147 kDa

Gen-ID: 55031

NCBI Accession: NM_017944, NP_060414

UniProt: B3KXF5

Pathways: Negative Regulation of intrinsic apoptotic Signaling