TNIP1 Antikörper (C-Term)

Produktnummer ABIN2774321

Produktdetails anti-TNIP1 Antikörper

Target: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Bindungsspezifität: C-Term

Reaktivität: Human, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NSRLFHLPEY TWRLPCGGVR NPNQSSQVMD PPTARPTEPE SPKNDREGPQ

Homologie: Dog: 92%, Horse: 86%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TNIP1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 636 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TNIP1

Target: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Andere Bezeichnung: TNIP1 (TNIP1 Produkte)

Hintergrund: TNIP1 interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal. TNIP1 increases cell surface CD4(T4) antigen expression. TNIP1 interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. TNIP1 may regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production.
Alias Symbols: ABIN-1, KIAA0113, NAF1, VAN, nip40-1
Protein Interaction Partner: HDDC3, MAGEB18, CFAP53, TXLNA, CCDC112, MOB3C, SYT6, TCEANC2, MOB1B, MAP1LC3A, NIFK, FAM161A, MAP1LC3B, TNIP3, SNIP1, CDIP1, NME7, MAGEH1, GABARAPL2, PNKP, MORF4L1, RALBP1, ZNHIT1, NDC80, TNIP1, OPTN, MORF4L2, AP1M1, TAX1BP1, ZBTB25, UBC, TNFAIP3, TCEA2,
Protein Size: 636

Molekulargewicht: 70 kDa

Gen-ID: 10318

NCBI Accession: NM_006058, NP_006049

UniProt: Q15025

Pathways: Activation of Innate immune Response