RAP2A Antikörper (N-Term)

Produktnummer ABIN2774388

Produktdetails anti-RAP2A Antikörper

Target: RAP2A (RAP2A, Member of RAS Oncogene Family (RAP2A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAP2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KYDPTIEDFY RKEIEVDSSP SVLEILDTAG TEQFASMRDL YIKNGQGFIL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RAP2A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 183 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RAP2A

Target: RAP2A (RAP2A, Member of RAS Oncogene Family (RAP2A))

Andere Bezeichnung: RAP2A (RAP2A Produkte)

Hintergrund: RAP2A is a small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.
Alias Symbols: K-REV, KREV, RAP2, RbBP-30
Protein Interaction Partner: UBC, RPTOR, ELAVL1, RRP9, TM7SF2, PLG, SERPINA1, FTL, FKBP2, ENSA, EEF1A1, NEDD4, TNIK, RUNDC3A, GRIN1, RASIP1, RAPGEF5, RAPGEF6, ARHGAP29, RASSF5, MAP4K4, BMPR1B, GRIN2D, RGS14, RALGDS, SMAD1, TGFBR1, RAP2A, RAF1, MLLT4, FNTB, ACVR1, RAPGEF4, RAPGEF3, RA
Protein Size: 183

Molekulargewicht: 20 kDa

Gen-ID: 5911

NCBI Accession: NM_021033, NP_066361

UniProt: P10114