EFTUD1 Antikörper (C-Term)

Produktnummer ABIN2774502

Produktdetails anti-EFTUD1 Antikörper

Target: EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EFTUD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TTEEEYLHFG EKADSENQAR KYMNAVRKRK GLYVEEKIVE HAEKQRTLSK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against EFTUD1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human EFTUD1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1069 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EFTUD1

Target: EFTUD1 (Elongation Factor Tu GTP Binding Domain Containing 1 (EFTUD1))

Andere Bezeichnung: EFTUD1 (EFTUD1 Produkte)

Synonyme: FAM42A antikoerper, HsT19294 antikoerper, RIA1 antikoerper, 4932434J20Rik antikoerper, 6030468D11Rik antikoerper, AI451340 antikoerper, AU019507 antikoerper, AU022896 antikoerper, D7Ertd791e antikoerper, elongation factor like GTPase 1 antikoerper, elongation factor like GPTase 1 antikoerper, EFL1 antikoerper, Efl1 antikoerper

Hintergrund: EFTUD1 is involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, EFTUD1 triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. EFTUD1 has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.
Alias Symbols: FAM42A, HsT19294, RIA1
Protein Interaction Partner: TP53RK, FKBP10, RPRD1B, OSGEP, PANK4, NSUN2, UFM1, KIAA1279, ACTR2, TPD52L2, RANGAP1, LPP, BAG1, UBC,
Protein Size: 1069

Molekulargewicht: 117 kDa

Gen-ID: 79631

NCBI Accession: NM_001040610, NP_001035700

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly