RGS11 Antikörper (Middle Region)

Produktnummer ABIN2774606

Produktdetails anti-RGS11 Antikörper

Target: RGS11 (Regulator of G-Protein Signaling 11 (RGS11))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LRQPHRYVLD DAQLHIYMLM KKDSYPRFLK SDMYKALLAE AGIPLEMKRR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against RGS11. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RGS11

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 446 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RGS11

Target: RGS11 (Regulator of G-Protein Signaling 11 (RGS11))

Andere Bezeichnung: RGS11 (RGS11 Produkte)

Synonyme: RS11 antikoerper, C78048 antikoerper, XRGSIV antikoerper, rgs9-a antikoerper, regulator of G protein signaling 11 antikoerper, regulator of G-protein signaling 11 antikoerper, regulator of G-protein signaling 11 L homeolog antikoerper, RGS11 antikoerper, Rgs11 antikoerper, rgs11.L antikoerper

Hintergrund: RGS11 belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form.The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.
Alias Symbols: RS11
Protein Interaction Partner: GNB5, ADRB2, SNTA1, HSP90AA1,
Protein Size: 446

Molekulargewicht: 51 kDa

Gen-ID: 8786

NCBI Accession: NM_003834, NP_003825

UniProt: Q4TT72

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling