ANAPC10 Antikörper (N-Term)

Produktnummer ABIN2774722

Produktdetails anti-ANAPC10 Antikörper

Target: ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Rind (Kuh), Kaninchen, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANAPC10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MTTPNKTPPG ADPKQLERTG TVREIGSQAV WSLSSCKPGF GVDQLRDDNL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against ANAPC10. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANAPC10

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 185 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ANAPC10 Antikörper (ABIN2774722)

Nourry, Maksumova, Pang, Liu, Wang: "Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1." in: BMC cell biology, Vol. 5, pp. 20, (2004) (PubMed).

Details zu ANAPC10

Target: ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))

Andere Bezeichnung: ANAPC10 (ANAPC10 Produkte)

Hintergrund: ANAPC10 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and sub
Alias Symbols: APC10, DKFZP564L0562, DOC1
Protein Interaction Partner: ANAPC4, DCPS, UBC, ANAPC15, MDC1, TP53BP1, LIG4, ANAPC1, ANAPC7, ANAPC2, CDC16, CDC23, CDC27, Gm9174, Cdc20, Bub1b, PPP2R1A, APC2, ANAPC11, SMAD3, SMAD2, LRP1, LRP8, LRP2,
Protein Size: 185

Molekulargewicht: 21 kDa

Gen-ID: 10393

NCBI Accession: NM_014885, NP_055700

UniProt: Q9UM13

Pathways: M Phase