RNF19A Antikörper (N-Term)
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- Target Alle RNF19A Antikörper anzeigen
- RNF19A (Ring Finger Protein 19A (RNF19A))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Hund, Pferd, Schwein, Rind (Kuh), Meerschweinchen, Kaninchen, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RNF19A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- IFSTNTSSDN GLTSISKQIG DFIECPLCLL RHSKDRFPDI MTCHHRSCVD
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against RNF19A. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human RNF19A
- Top Product
- Discover our top product RNF19A Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 838 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RNF19A (Ring Finger Protein 19A (RNF19A))
- Andere Bezeichnung
- RNF19A (RNF19A Produkte)
- Synonyme
- RNF19 antikoerper, RNF19A antikoerper, AA032313 antikoerper, Dorfin antikoerper, Rnf19 antikoerper, UIP117 antikoerper, Ubce7ip2 antikoerper, XYbp antikoerper, ring finger protein 19A, RBR E3 ubiquitin protein ligase antikoerper, ring finger protein 19A antikoerper, RNF19A antikoerper, Rnf19a antikoerper
- Hintergrund
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RNF19A contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB.The protein encoded this gene contains two RING-finger motifs and an IBR (in between RING fingers) motif. This protein is an E3 ubiquintin ligase that is localized in Lewy bodies (LBs), a characteristic neuronal inclusion in Parkinson's disease (PD) brains. This protein interacts with UBE2L3/UBCH7 and UBE2E2/UBCH8, but not other ubiquitin-conjugating enzymes. This protein is found to bind and ubiquitylate synphilin 1 (SNCAIP), which is a interacting protein of alpha synuclein in neurons, and a major component of LB. Alternatively spliced transcript variants encoding the same protein have been reported.
Alias Symbols: DKFZp566B1346, DORFIN, RNF19
Protein Interaction Partner: UBC, UBE2L3, Psmc3, ZAK, NUDT21, C11orf58, RPS6KA5, MAP3K7, ILK, SOD1, VCP, SNCAIP, CASR, UBE2E2, SUFU, TUBG2, UBE2L6, TUBG1,
Protein Size: 838 - Molekulargewicht
- 91 kDa
- Gen-ID
- 25897
- NCBI Accession
- NM_015435, NP_056250
- UniProt
- Q9NV58
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