MARCH5 Antikörper (N-Term)
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- Target Alle MARCH5 Antikörper anzeigen
- MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MARCH5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- CRGSTKWVHQ ACLQRWVDEK QRGNSTARVA CPQCNAEYLI VFPKLGPVVY
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against MARCH5. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MARCH5
- Top Product
- Discover our top product MARCH5 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 278 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Inactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagy." in: Biochimica et biophysica acta, Vol. 1843, Issue 7, pp. 1295-307, (2014) (PubMed).
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Inactivation of Omi/HtrA2 protease leads to the deregulation of mitochondrial Mulan E3 ubiquitin ligase and increased mitophagy." in: Biochimica et biophysica acta, Vol. 1843, Issue 7, pp. 1295-307, (2014) (PubMed).
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- Target
- MARCH5 (Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5))
- Andere Bezeichnung
- MARCH5 (MARCH5 Produkte)
- Synonyme
- march5 antikoerper, MARCH5 antikoerper, mitol antikoerper, rnf153 antikoerper, march-v antikoerper, zgc:162966 antikoerper, MARCH-V antikoerper, Mar-05 antikoerper, MITOL antikoerper, RNF153 antikoerper, 1810015H18Rik antikoerper, 2310008I22Rik antikoerper, 2700055A20Rik antikoerper, 5730499H23Rik antikoerper, E130202O05Rik antikoerper, Marchv antikoerper, Rnf153 antikoerper, membrane-associated ring finger (C3HC4) 5 antikoerper, membrane associated ring-CH-type finger 5 antikoerper, membrane associated ring-CH-type finger 5 L homeolog antikoerper, march5 antikoerper, MARCH5 antikoerper, march5.L antikoerper, March5 antikoerper
- Hintergrund
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MARCH5 is an ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2) and DRP1 (DNM1L). MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2, MIM 608507) and DRP1 (DNM1L, MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1502 AK000452.1 3-1504 1503-1863 BC015480.1 1463-1823 1864-1901 BE393612.1 438-475 1902-3713 BC015480.1 1852-3663 3714-3941 BC015480.1 3669-3896
Alias Symbols: FLJ20445, MARCH-V, MITOL, RNF153
Protein Interaction Partner: FATE1, UBE2W, UBC, DNM1L, MFN2, UBE2E1, FIS1, UBE2E3, MFN1, PARK2, MARCH5, CCNB1, UBE2D3, UBE2D2, UBE2D1, MAP1B, KIAA0368, SOD1, MAVS, TANK, TRAF6, AKTIP, UBE2T, UBE2N, UBE2I, UTRN,
Protein Size: 278 - Molekulargewicht
- 31 kDa
- Gen-ID
- 54708
- NCBI Accession
- NM_017824, NP_060294
- UniProt
- Q9NX47
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