RNF128 Antikörper (C-Term)
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- Target Alle RNF128 Antikörper anzeigen
- RNF128 (Ring Finger Protein 128 (RNF128))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RNF128 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LEEHVQSTNE SLQLVNHEAN SVAVDVIPHV DNPTFEEDET PNQETAVREI
- Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against RNF128. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human RNF128
- Top Product
- Discover our top product RNF128 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 428 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RNF128 (Ring Finger Protein 128 (RNF128))
- Andere Bezeichnung
- RNF128 (RNF128 Produkte)
- Synonyme
- rnf128 antikoerper, wu:fb57h05 antikoerper, zgc:77843 antikoerper, 1300002C13Rik antikoerper, AI987883 antikoerper, GRAIL antikoerper, Greul1 antikoerper, RGD1566282 antikoerper, grail antikoerper, greul1 antikoerper, ring finger protein 128a antikoerper, ring finger protein 128, E3 ubiquitin protein ligase antikoerper, ring finger protein 128 antikoerper, ring finger protein 128, E3 ubiquitin protein ligase L homeolog antikoerper, rnf128a antikoerper, RNF128 antikoerper, Rnf128 antikoerper, rnf128.L antikoerper
- Hintergrund
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RNF128 is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of RNF128 in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of RNF128 was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype.The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: FLJ23516, GRAIL
Protein Interaction Partner: CEP76, APPBP2, TP53, UBE2H, UBE2E1, UBE2D1, Arhgdia, Arhgdib, RNF128, UBE2T, UBE2I, UBE2N, CD40LG, OTUB1, USP8,
Protein Size: 428 - Molekulargewicht
- 47 kDa
- Gen-ID
- 79589
- NCBI Accession
- NM_194463, NP_919445
- UniProt
- Q8TEB7
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