GJC2 Antikörper (Middle Region)

Produktnummer ABIN2774865

Produktdetails anti-GJC2 Antikörper

Target: GJC2 (Gap Junction Protein, gamma 2, 47kDa (GJC2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GJC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: APASRTGSAT SAGTVGEQGR PGTHERPGAK PRAGSEKGSA SSRDGKTTVW

Homologie: Human: 100%, Rabbit: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GJC2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GJC2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 439 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GJC2

Target: GJC2 (Gap Junction Protein, gamma 2, 47kDa (GJC2))

Andere Bezeichnung: GJC2 (GJC2 Produkte)

Synonyme: GJA12 antikoerper, cx47 antikoerper, gja12 antikoerper, cx46.6 antikoerper, pmldar antikoerper, MGC146420 antikoerper, B230382L12Rik antikoerper, Cx47 antikoerper, Gja12 antikoerper, CX46.6 antikoerper, HLD2 antikoerper, LMPH1C antikoerper, PMLDAR antikoerper, SPG44 antikoerper, gap junction protein gamma 2 antikoerper, si:dkey-91f15.1 antikoerper, gap junction protein, gamma 2 antikoerper, GJC2 antikoerper, gjc2 antikoerper, si:dkey-91f15.1 antikoerper, Gjc2 antikoerper

Hintergrund: GJC2 is a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.This gene encodes a gap junction protein. Gap junction proteins are members of a large family of homologous connexins and comprise 4 transmembrane, 2 extracellular, and 3 cytoplasmic domains. This gene plays a key role in central myelination and is involved in peripheral myelination in humans. Defects in this gene are the cause of autosomal recessive Pelizaeus-Merzbacher-like disease-1.
Alias Symbols: CX46.6, Cx47, GJA12, MGC105119, PMLDAR, HLD2, SPG44, LMPH1C
Protein Interaction Partner: ALB,
Protein Size: 439

Molekulargewicht: 47 kDa

Gen-ID: 57165

NCBI Accession: NM_020435, NP_065168

UniProt: Q5T442