TJP1 Antikörper (Middle Region)

Produktnummer ABIN2774876

Produktdetails anti-TJP1 Antikörper

Target: TJP1 (Tight Junction Protein 1 (TJP1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Schwein, Hund, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TJP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: QNHVLKQPAV SHPGHRPDKE PNLTYEPQLP YVEKQASRDL EQPTYRYESS

Homologie: Dog: 92%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 87%, Pig: 93%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TJP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TJP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1668 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TJP1

Target: TJP1 (Tight Junction Protein 1 (TJP1))

Andere Bezeichnung: TJP1 (TJP1 Produkte)

Hintergrund: TJP1 is a protein located on a cytoplasmic membrane surface of intercellular tight junctions. TJP1 may be involved in signal transduction at cell-cell junctions.This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: DKFZp686M05161, MGC133289, ZO-1
Protein Interaction Partner: VMP1, RAPGEF2, LATS2, TJP2, PAN2, DTNA, UBC, SCO2, VAPA, VAPB, ZPR1, NOTCH2, NDUFV2, NDUFS6, SUGP1, RTN4, STRN, PARD3, PARD6A, PRKCI, SIRT7, KHDRBS1, ELAVL1, SSTR3, Cdk1, TUBA1C, TUBB4A, VIM, SPTAN1, PLEC, KRT10, KRT8, KRT1, GJA1, FLNA, ANXA6, ACTN1, ACTN
Protein Size: 1668

Molekulargewicht: 187 kDa

Gen-ID: 7082

NCBI Accession: NM_175610, NP_783297

UniProt: Q07157

Pathways: Carbohydrate Homeostasis, Cell-Cell Junction Organization