MCM7 Antikörper (Middle Region)
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- Target Alle MCM7 Antikörper anzeigen
- MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Kaninchen, Meerschweinchen, Rind (Kuh), Pferd, Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MCM7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LSTALARLRM VDVVEKEDVN EAIRLMEMSK DSLLGDKGQT ARTQRPADVI
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against MCM7. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human MCM7
- Top Product
- Discover our top product MCM7 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 719 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
- Andere Bezeichnung
- MCM7 (MCM7 Produkte)
- Synonyme
- CDC47 antikoerper, MCM2 antikoerper, P1.1-MCM3 antikoerper, P1CDC47 antikoerper, P85MCM antikoerper, PNAS146 antikoerper, MCM7 antikoerper, AI747533 antikoerper, Mcmd7 antikoerper, mCDC47 antikoerper, chunp6911 antikoerper, nyz175 antikoerper, sr:nyz175 antikoerper, cdc47 antikoerper, cdc47-2 antikoerper, mcm7 antikoerper, xmcm7 antikoerper, CG4978 antikoerper, DmMCM7 antikoerper, DmeMCM7 antikoerper, Dmel\\CG4978 antikoerper, McM7 antikoerper, Mcp-PCR1 antikoerper, PCR1 antikoerper, anon-EST:Liang-1.66 antikoerper, clone 1.66 antikoerper, minichromosome maintenance complex component 7 antikoerper, mini-chromosome maintenance complex protein 7 antikoerper, minichromosome maintenance complex component 2 antikoerper, minichromosome maintenance complex component 7 L homeolog antikoerper, Minichromosome maintenance 7 antikoerper, minichromosome maintenance complex component 7 S homeolog antikoerper, MCM complex subunit Mcm7 antikoerper, MCM7 antikoerper, CDC47 antikoerper, Mcm7 antikoerper, MCM2 antikoerper, mcm7 antikoerper, mcm7.L antikoerper, mcm7.S antikoerper
- Hintergrund
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MCM7 encodes a protein that is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: CDABP0042, CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS-146, PNAS146
Protein Interaction Partner: AK8, MIPOL1, C8orf34, USHBP1, MCMBP, CCDC102B, TRIM54, MBIP, UBQLN1, TRIM27, NAB2, KIFC3, GOLGA2, PNMA1, UBC, SP2, HAUS2, CEP250, CEP57, SUMO2, SUMO3, PCNA, STAU1, SUZ12, RNF2, MCM4, MCM2, HSP90AB1, PRMT1, PRRC1, CLUH, TOMM34, TRIM16, HYOU1, BAG3, MIB1, P
Protein Size: 719 - Molekulargewicht
- 81 kDa
- Gen-ID
- 4176
- NCBI Accession
- NM_005916, NP_005907
- UniProt
- P33993
- Pathways
- DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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