THO Complex 4 Antikörper (N-Term)

Produktnummer ABIN2774915

Produktdetails anti-THO Complex 4 Antikörper

Target: THO Complex 4 (THOC4)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser THO Complex 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: GGGPIRNRPA IARGAAGGGG RNRPAPYSRP KQLPDKWQHD LFDSGFGGGA

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against THOC4. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human THOC4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 257 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-THO Complex 4 Antikörper (ABIN2774915)

Ding, Enriquez-Algeciras, Dave, Perez-Pinzon, Bhattacharya: "The role of deimination in ATP5b mRNA transport in a transgenic mouse model of multiple sclerosis." in: EMBO reports, Vol. 13, Issue 3, pp. 230-6, (2012) (PubMed).

Strässer, Masuda, Mason, Pfannstiel, Oppizzi, Rodriguez-Navarro, Rondón, Aguilera, Struhl, Reed, Hurt: "TREX is a conserved complex coupling transcription with messenger RNA export." in: Nature, Vol. 417, Issue 6886, pp. 304-8, (2002) (PubMed).

Details zu THO Complex 4

Target: THO Complex 4 (THOC4)

Andere Bezeichnung: THOC4 (THOC4 Produkte)

Synonyme: THOC4 antikoerper, Aly antikoerper, ALY antikoerper, ALY/REF antikoerper, BEF antikoerper, REF antikoerper, tho4 antikoerper, thoc4 antikoerper, zgc:171753 antikoerper, Tho4-A antikoerper, alyref-a antikoerper, thoc4-a antikoerper, REF1 antikoerper, Refbp1 antikoerper, Thoc4 antikoerper, Tho4 antikoerper, Aly/REF export factor antikoerper, THO complex 4 antikoerper, Aly/REF export factor L homeolog antikoerper, ALYREF antikoerper, Thoc4 antikoerper, alyref antikoerper, alyref.L antikoerper, Alyref antikoerper

Hintergrund: THOC4 is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.The protein encoded by this gene is a heat stable, nuclear protein and functions as a molecular chaperone. It is thought to regulate dimerization, DNA binding, and transcriptional activity of basic region-leucine zipper (bZIP) proteins.
Alias Symbols: ALY, BEF, REF, THOC4, ALY/REF
Protein Interaction Partner: TP53, AKT1, NEDD1, THOC3, NCBP1, THOC2, CEP250, THOC5, DDX39B, STAU1, UBC, MDM2, SUZ12, EED, RNF2, FBXO6, CD81, ICAM1, IGSF8, PAN2, VCAM1, ITGA4, IL7R, FN1, CBX8, EIF4A3, MAGOH, PAXIP1, TRIP12, TRIP13, UBE2I, SF3B4, TLE3, YBX1, HNRNPM, ERCC4, ATP6V1E1, UB
Protein Size: 257

Molekulargewicht: 28 kDa

Gen-ID: 10189

NCBI Accession: NM_005782, NP_005773

UniProt: Q86V81