STUB1 Antikörper (N-Term)
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- Target Alle STUB1 Antikörper anzeigen
- STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser STUB1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- MKGKEEKEGG ARLGAGGGSP EKSPSAQELK EQGNRLFVGR KYPEAAACYG
- Homologie
- Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against STUB1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human STUB1
- Top Product
- Discover our top product STUB1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 303 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))
- Andere Bezeichnung
- STUB1 (STUB1 Produkte)
- Synonyme
- CHIP antikoerper, HSPABP2 antikoerper, NY-CO-7 antikoerper, SDCCAG7 antikoerper, UBOX1 antikoerper, 0610033N24Rik antikoerper, 2210017D18Rik antikoerper, 2310040B03Rik antikoerper, AW046544 antikoerper, Chip antikoerper, wu:fc22f04 antikoerper, zgc:56076 antikoerper, STUB1 antikoerper, chip antikoerper, ATCHIP antikoerper, CARBOXYL TERMINUS OF HSC70-INTERACTING PROTEIN antikoerper, carboxyl terminus of HSC70-interacting protein antikoerper, STIP1 homology and U-box containing protein 1 antikoerper, STIP1 homology and U-Box containing protein 1 antikoerper, STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase L homeolog antikoerper, STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase antikoerper, STIP1 homology and U box-containing protein 1 antikoerper, carboxyl terminus of HSC70-interacting protein antikoerper, STUB1 antikoerper, Stub1 antikoerper, stub1 antikoerper, stub1.L antikoerper, LOC100282870 antikoerper, CHIP antikoerper
- Hintergrund
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STUB1 modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. It has E3 ubiquitin-protein ligase activity and targets misfolded chaperone substrates towards proteasomal degradation. STUB1 mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation.
Alias Symbols: CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1
Protein Interaction Partner: HSP90AA1, HSPA8, PCSK9, OLFM3, ATCAY, CCL28, UBE2Q1, TXN2, RUSC1, HSPA1B, FMR1, ERN1, STUB1, UBE2V1, UBE2N, UBE2D3, UBE2D1, UBC, TP53, MAPT, MAP3K11, SNAI2, BAG1, HSPA4L, CDC37, DNAJB6, BAG2, BAG3, BAG4, MLF2, HSP90AB1, HSPA4, HSPA2, HSPA1L, ENDOG, TXLNG,
Protein Size: 303 - Molekulargewicht
- 35 kDa
- Gen-ID
- 10273
- NCBI Accession
- NM_005861, NP_005852
- UniProt
- Q9UNE7
- Pathways
- Regulation of Hormone Metabolic Process, Response to Water Deprivation
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