DDX17 Antikörper (N-Term)

Produktnummer ABIN2775206

Produktdetails anti-DDX17 Antikörper

Target: DDX17 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 17 (DDX17))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Pferd, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDX17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PKKFGNPGER LRKKKWDLSE LPKFEKNFYV EHPEVARLTP YEVDELRRKK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against DDX17. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DDX17

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 729 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DDX17

Target: DDX17 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 17 (DDX17))

Andere Bezeichnung: DDX17 (DDX17 Produkte)

Synonyme: MGC80019 antikoerper, DDX17 antikoerper, P72 antikoerper, RH70 antikoerper, Cp68 antikoerper, DDX46 antikoerper, 2610007K22Rik antikoerper, A430025E01Rik antikoerper, AI047725 antikoerper, C80929 antikoerper, Gm926 antikoerper, p72 antikoerper, DEAD-box helicase 17 L homeolog antikoerper, probable ATP-dependent RNA helicase DDX17 antikoerper, DEAD-box helicase 17 antikoerper, DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 antikoerper, ddx17.L antikoerper, LOC412313 antikoerper, DDX17 antikoerper, ddx17 antikoerper, Ddx17 antikoerper

Hintergrund: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The DEAD box protein is an ATPase activated by a variety of RNA species but not by dsDNA. This protein and that encoded by DDX5 gene are more closely related to each other than to any other member of the DEAD box family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and splicesosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an ATPase activated by a variety of RNA species, but not by dsDNA. This protein, and that encoded by DDX5 gene, are more closely related to each other than to any other member of the DEAD box family. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene.
Alias Symbols: DKFZp761H2016, P72, RH70
Protein Interaction Partner: BYSL, GRB2, RBM15, CEP250, UBC, SUMO2, SUMO3, SPRTN, STAU1, CDC37, IVNS1ABP, SUMO1, LGR4, MDM2, NEDD8, RPA3, RPA2, RPA1, WWOX, EED, rev, P3H1, LSM1, PRPSAP1, PIN1, DDX5, APBB1, PARK2, FBXO6, TARDBP, WBP11, SF1, UBD, IGSF8, ICAM1, CD81, SF3B4, WHSC1, VCAM1
Protein Size: 729

Molekulargewicht: 80 kDa

Gen-ID: 10521

NCBI Accession: NM_006386, NP_006377

UniProt: Q92841

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Muscle Cell Differentiation