SNRNP200 Antikörper (N-Term)

Produktnummer ABIN2775221

Produktdetails anti-SNRNP200 Antikörper

Target: SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNRNP200 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GDEDVYGEVR EEASDDDMEG DEAVVRCTLS ANLVASGELM SSKKKDLHPR

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SNRNP200. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 2136 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SNRNP200

Target: SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))

Andere Bezeichnung: SNRNP200 (SNRNP200 Produkte)

Synonyme: ASCC3L1 antikoerper, BRR2 antikoerper, HELIC2 antikoerper, RP33 antikoerper, U5-200KD antikoerper, small nuclear ribonucleoprotein U5 subunit 200 antikoerper, SNRNP200 antikoerper

Hintergrund: Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa.
Alias Symbols: ASCC3L1, BRR2, FLJ11521, HELIC2, RP33, U5-200KD
Protein Interaction Partner: PRPF8, EMD, CDKN1A, SUMO2, STAU1, UBC, SUMO1, LGR4, WWOX, RPA3, RPA2, RPA1, ERG, SUZ12, EZH2, EED, RNF2, rev, ELP3, KIAA1033, WDHD1, POLR2H, PIN1, USP34, TSC22D1, PARK2, FBXO6, TARDBP, PRPF4B, UBD, USP19, LSM8, SNRNP200, SF3B2, RBM5, ITGA4, FN1, RNF113A,
Protein Size: 2136

Molekulargewicht: 244 kDa

Gen-ID: 23020

NCBI Accession: NM_014014, NP_054733

UniProt: O75643

Pathways: Ribonucleoprotein Complex Subunit Organization