IFIH1 Antikörper (Middle Region)
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- Target Alle IFIH1 Antikörper anzeigen
- IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Schwein, Rind (Kuh), Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IFIH1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- QINDTIRMID AYTHLETFYN EEKDKKFAVI EDDSDEGGDD EYCDGDEDED
- Homologie
- Cow: 85%, Horse: 85%, Human: 100%, Mouse: 77%, Pig: 77%, Rat: 82%
- Produktmerkmale
- This is a rabbit polyclonal antibody against IFIH1. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human IFIH1
- Top Product
- Discover our top product IFIH1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1025 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IFIH1 (Interferon Induced with Helicase C Domain 1 (IFIH1))
- Andere Bezeichnung
- IFIH1 (IFIH1 Produkte)
- Synonyme
- MDA5 antikoerper, Hlcd antikoerper, IDDM19 antikoerper, MDA-5 antikoerper, RLR-2 antikoerper, 9130009C22Rik antikoerper, Helicard antikoerper, RGD1560496 antikoerper, interferon induced with helicase C domain 1 antikoerper, IFIH1 antikoerper, Ifih1 antikoerper
- Hintergrund
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DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. IFIH1 is a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation.DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents, treatment with either agent alone only achieves reversible differentiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: Hlcd, IDDM19, MDA-5, MDA5, MGC133047
Protein Interaction Partner: USP21, USP3, UBC, NLRC5, APP, TSPAN6, MAVS, PCBP2, PIAS2, SUMO1, IDE,
Protein Size: 1025 - Molekulargewicht
- 117 kDa
- Gen-ID
- 64135
- NCBI Accession
- NM_022168, NP_071451
- UniProt
- Q9BYX4
- Pathways
- Activation of Innate immune Response
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