CES2 Antikörper (C-Term)

Produktnummer ABIN2775271

Produktdetails anti-CES2 Antikörper

Target: CES2 (Carboxylesterase 2 (CES2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CES2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: HWPLFDQEEQ YLQLNLQPAV GRALKAHRLQ FWKKALPQKI QELEEPEERH

Homologie: Dog: 83%, Guinea Pig: 83%, Human: 100%, Mouse: 83%, Rat: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against CES2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CES2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 623 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CES2 Antikörper (ABIN2775271)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Details zu CES2

Target: CES2 (Carboxylesterase 2 (CES2))

Andere Bezeichnung: CES2 (CES2 Produkte)

Synonyme: CE-2 antikoerper, CES2A1 antikoerper, PCE-2 antikoerper, iCE antikoerper, Ces2 antikoerper, im:6908784 antikoerper, si:dkey-38l12.2 antikoerper, zgc:153863 antikoerper, ce-2 antikoerper, ces2a1 antikoerper, pce-2 antikoerper, carboxylesterase 2 antikoerper, liver carboxylesterase 2 antikoerper, cocaine esterase antikoerper, carboxylesterase 2 (intestine, liver) antikoerper, CES2 antikoerper, Ces2 antikoerper, LOC100343300 antikoerper, LOC100734360 antikoerper, ces2 antikoerper

Hintergrund: Carboxylesterase 2 is a member of a large multigene family. The enzymes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined, however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system.Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined, however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: CE-2, iCE, PCE-2, CES2A1
Protein Size: 623

Molekulargewicht: 69 kDa

Gen-ID: 8824

NCBI Accession: NM_003869, NP_003860

UniProt: O00748