RAD23A Antikörper (N-Term)
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- Target Alle RAD23A Antikörper anzeigen
- RAD23A (RAD23 Homolog A (RAD23A))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Kaninchen, Pferd, Meerschweinchen, Rind (Kuh)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RAD23A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- VPSSGSSGRE EDAASTLVTG SEYETMLTEI MSMGYERERV VAALRASYNN
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against RAD23A. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human RAD23A
- Top Product
- Discover our top product RAD23A Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 363 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RAD23A (RAD23 Homolog A (RAD23A))
- Andere Bezeichnung
- RAD23A (RAD23A Produkte)
- Synonyme
- rad23a antikoerper, wu:fe11h06 antikoerper, zgc:92001 antikoerper, RAD23A antikoerper, HHR23A antikoerper, HR23A antikoerper, 2310040P19Rik antikoerper, AL024030 antikoerper, mHR23A antikoerper, RAD23 homolog A, nucleotide excision repair protein a antikoerper, RAD23 homolog A, nucleotide excision repair protein antikoerper, rad23aa antikoerper, RAD23A antikoerper, Rad23a antikoerper
- Hintergrund
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RAD23A is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Alias Symbols: HHR23A, MGC111083
Protein Interaction Partner: USP25, ZBTB44, TRIP6, TRAF5, TRAF2, ZBTB8A, ANKRD40, FAM188A, TRIM54, NGLY1, CEP250, CEP76, UBC, SHFM1, vpr, XPC, DCTPP1, OGFOD1, UBA6, UBE2R2, TRNT1, HERC4, NT5C2, FKBP9, PCNA, HEXA, CDC34, GNPDA1, GTF3C4, USP5, WARS, TBCE, PYGL, PARP1, SH3RF2, PARK2, SQ
Protein Size: 363 - Molekulargewicht
- 40 kDa
- Gen-ID
- 5886
- NCBI Accession
- NM_005053, NP_005044
- UniProt
- P54725
- Pathways
- DNA Reparatur
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