Peroxidasin Antikörper (N-Term)

Produktnummer ABIN2775373

Produktdetails anti-Peroxidasin Antikörper

Target: Peroxidasin (PXDN) (Peroxidasin Homolog (PXDN))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Meerschweinchen, Pferd, Hund, Kaninchen, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Peroxidasin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NLKYLYLYKN EIQSIDRQAF KGLASLEQLY LHFNQIETLD PDSFQHLPKL

Homologie: Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PXDN. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PXDN

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Peroxidasin

Target: Peroxidasin (PXDN) (Peroxidasin Homolog (PXDN))

Andere Bezeichnung: PXDN (PXDN Produkte)

Synonyme: D2S448 antikoerper, D2S448E antikoerper, MG50 antikoerper, PRG2 antikoerper, PXN antikoerper, VPO antikoerper, 2310075M15Rik antikoerper, C85409 antikoerper, E330004E07 antikoerper, VPO1 antikoerper, mKIAA0230 antikoerper, peroxidasin antikoerper, PXDN antikoerper, Pxdn antikoerper

Hintergrund: Drosophila peroxidasin is an extracellular matrix-associated peroxidase (Horikoshi et al., 1999 [PubMed 10441517]). It is expressed exclusively in hemocytes derived from head mesoderm at a very early stage of differentiation. Peroxidasin exists as a homotrimer with a unique hybrid structure that combines an enzymatically functional peroxidase domain with motifs that are typically found in extracellular matrix-associated proteins. It is a secreted protein that contains a secretory recognition sequence at its N terminus. Peroxidasin catalyzes hydrogen peroxide-driven radioiodination, oxidations, and the formation of dityrosine in vitro. It is also thought to function in extracellular matrix consolidation, phagocytosis, and defense.
Protein Interaction Partner: HECW2, BNIPL, FBXO6, TRAF4,
Protein Size: 727

Molekulargewicht: 79 kDa

Gen-ID: 7837