MFN2 Antikörper (N-Term)
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- Target Alle MFN2 Antikörper anzeigen
- MFN2 (Mitofusin 2 (MFN2))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MFN2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- STVINAMLWD KVLPSGIGHT TNCFLRVEGT DGHEAFLLTE GSEEKRSAKT
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%
- Produktmerkmale
- This is a rabbit polyclonal antibody against MFN2. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MFN2
- Top Product
- Discover our top product MFN2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 757 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MFN2 (Mitofusin 2 (MFN2))
- Andere Bezeichnung
- MFN2 (MFN2 Produkte)
- Synonyme
- CG3869 antikoerper, Dmel\\CG3869 antikoerper, MARF antikoerper, Marf-1 antikoerper, Mfn antikoerper, anon-WO0125274.3 antikoerper, dMFN antikoerper, dMfn antikoerper, dmfn antikoerper, marf antikoerper, mfn antikoerper, mfn2 antikoerper, MFN2 antikoerper, hsg antikoerper, cmt2a antikoerper, cprp1 antikoerper, cmt2a2 antikoerper, CMT2A antikoerper, CMT2A2 antikoerper, CPRP1 antikoerper, HSG antikoerper, D630023P19Rik antikoerper, Fzo antikoerper, mg:cb01g09 antikoerper, si:dkeyp-104h9.2 antikoerper, wu:fb79a11 antikoerper, mitofusin 2 antikoerper, Mitochondrial assembly regulatory factor antikoerper, mitofusin-2 antikoerper, mitofusin 2 L homeolog antikoerper, MFN2 antikoerper, Marf antikoerper, mfn2 antikoerper, LOC100186475 antikoerper, Mfn2 antikoerper, mfn2.L antikoerper
- Hintergrund
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MFN2 is a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. It is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke.This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
Alias Symbols: CMT2A, CMT2A2, CPRP1, HSG, KIAA0214, MARF
Protein Interaction Partner: UBC, MARCH5, PARK2, UBE2N, MFN2, TER94, MAVS, vpr, HUWE1, MAPK9,
Protein Size: 757 - Molekulargewicht
- 86 kDa
- Gen-ID
- 9927
- NCBI Accession
- NM_014874, NP_055689
- UniProt
- O95140
- Pathways
- Skeletal Muscle Fiber Development
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