ANO1 Antikörper (Middle Region)

Produktnummer ABIN2775453

Produktdetails anti-ANO1 Antikörper

Target: ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HGFVNHTLSS FNVSDFQNGT APNDPLDLGY EVQICRYKDY REPPWSENKY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 79%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TMEM16A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TMEM16A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 960 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ANO1 Antikörper (ABIN2775453)

Liu, Zhang, Huang, Qi, Xu, Gao, Du, Gamper, Zhang: "Characterization of the effects of Cl⁻ channel modulators on TMEM16A and bestrophin-1 Ca²⁺ activated Cl⁻ channels." in: Pflügers Archiv : European journal of physiology, Vol. 467, Issue 7, pp. 1417-1430, (2015) (PubMed).

Banga, Flaig, Lewis, Winfree, Blazer-Yost: "Epinephrine stimulation of anion secretion in the Calu-3 serous cell model." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 306, Issue 10, pp. L937-46, (2014) (PubMed).

Details zu ANO1

Target: ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))

Andere Bezeichnung: TMEM16A (ANO1 Produkte)

Synonyme: DOG1 antikoerper, ORAOV2 antikoerper, TAOS2 antikoerper, TMEM16A antikoerper, Tmem16a antikoerper, anoctamin 1 antikoerper, anoctamin 1, calcium activated chloride channel antikoerper, Ano1 antikoerper, ANO1 antikoerper

Hintergrund: TMEM16A belongs to the anoctamin family. TMEM16A acts as a calcium-activated chloride channel. It is required for normal tracheal development.
Alias Symbols: FLJ10261, ORAOV2, TAOS2, CACC, DOG1, TMEM16A, ANO1
Protein Interaction Partner: UBC,
Protein Size: 960

Molekulargewicht: 111 kDa

Gen-ID: 55107

NCBI Accession: NM_018043, NP_060513

UniProt: Q5XXA6