PARD6A Antikörper (N-Term)

Produktnummer ABIN2775615

Produktdetails anti-PARD6A Antikörper

Target: PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARD6A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MARPQRTPAR SPDSIVEVKS KFDAEFRRFA LPRASVSGFQ EFSRLLRAVH

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PARD6A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PARD6A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 345 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PARD6A

Target: PARD6A (Par-6 Partitioning Defective 6 Homolog alpha (PARD6A))

Andere Bezeichnung: PARD6A (PARD6A Produkte)

Synonyme: PARD6A antikoerper, 0710008C04Rik antikoerper, 2610010A15Rik antikoerper, PAR6alpha antikoerper, Par-6 antikoerper, Par6 antikoerper, Par6c antikoerper, TAX40 antikoerper, Tip-40 antikoerper, Par-6a antikoerper, Par6a antikoerper, PAR-6A antikoerper, PAR6 antikoerper, PAR6C antikoerper, TIP-40 antikoerper, par-6 partitioning defective 6 homolog alpha (C. elegans) antikoerper, par-6 family cell polarity regulator alpha antikoerper, Partitioning defective protein 6 antikoerper, PARD6A antikoerper, Pard6a antikoerper, par-6 antikoerper

Hintergrund: This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40
Protein Interaction Partner: PRKCI, WDR83, PRKCZ, FBXO31, PARD3, UBC, TUBG1, ARHGAP17, VHL, MAP2K5, TJP1, SMURF1, TGFB1, WDR92, PARD6B, PDRG1, RPAP3, MARK4, PIH1D1, SUGT1, YWHAZ, YWHAH, LLGL1, LLGL2, MARK2, CDC42, CRB3, ECT2, PLCB1, RHOQ, PRKCH, RAC1, CDH5, PLCB3, TGFBR1, TCP10, PRKC
Protein Size: 345

Molekulargewicht: 37 kDa

Gen-ID: 50855

NCBI Accession: NM_001037281, NP_001032358

UniProt: Q3TY70

Pathways: Cell-Cell Junction Organization