PARD3 Antikörper (Middle Region)

Produktnummer ABIN2775627

Produktdetails anti-PARD3 Antikörper

Target: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: EQQMKKQPPS EGPSNYDSYK KVQDPSYAPP KGPFRQDVPP SPSQVARLNR

Homologie: Guinea Pig: 79%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PARD3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PARD3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1356 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PARD3

Target: PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

Andere Bezeichnung: PARD3 (PARD3 Produkte)

Hintergrund: PARD proteins, which were first identified in C. elegans, are essential for asymmetric cell division and polarized growth, whereas CDC42 (MIM 116952) mediates the establishment of cell polarity. The CDC42 GTPase, which is controlled by nucleotide exchange
Alias Symbols: ASIP, Baz, Bazooka, FLJ21015, PAR3, PAR3alpha, PARD3A, SE2-5L16, SE2-5LT1, SE2-5T2
Protein Interaction Partner: UBC, AMOTL2, LATS2, YAP1, LATS1, YWHAB, INADL, PRKCI, GAB1, MARK2, PARD6A, YWHAE, AMOT, ARHGAP17, VHL, TJP1, Smurf1, Smurf2, ANP32E, PSME3, RPS18, RPS3, PSME2, PFKP, KPNA4, HSPD1, HSPA8, HSPA6, SIAH1, PARD6B, PARD6G, CCDC88A, RASSF8, PNMA2, DCAF7, PNMA1,
Protein Size: 1356

Molekulargewicht: 151 kDa

Gen-ID: 56288

NCBI Accession: NM_019619, NP_062565

UniProt: Q8TEW0

Pathways: Cell-Cell Junction Organization