PARD6B Antikörper (N-Term)

Produktnummer ABIN2775630

Produktdetails anti-PARD6B Antikörper

Target: PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARD6B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SKFGAEFRRF SLERSKPGKF EEFYGLLQHV HKIPNVDVLV GYADIHGDLL

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against Pard6b. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of MOUSE Pard6b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PARD6B

Target: PARD6B (Par-6 Partitioning Defective 6 Homolog beta (PARD6B))

Andere Bezeichnung: Pard6b (PARD6B Produkte)

Synonyme: PARD6B antikoerper, AV025615 antikoerper, Par6b antikoerper, PAR6B antikoerper, par-6 antikoerper, par6 antikoerper, pard6beta antikoerper, si:dkey-192i18.6 antikoerper, PAR-6 antikoerper, PAR-6B antikoerper, par-6 family cell polarity regulator beta antikoerper, par-6 family cell polarity regulator beta S homeolog antikoerper, par-6 partitioning defective 6 homolog beta (C. elegans) antikoerper, PARD6B antikoerper, Pard6b antikoerper, pard6b.S antikoerper, pard6b antikoerper

Hintergrund: Pard6b is a adapter protein involved in asymmetrical cell division and cell polarization processes. It is probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Alias Symbols: AV025615, Par6b
Protein Interaction Partner: Llgl1,
Protein Size: 371

Molekulargewicht: 40 kDa

Gen-ID: 58220

NCBI Accession: NM_021409, NP_067384

UniProt: Q9JK83

Pathways: Cell-Cell Junction Organization