AMOTL1 Antikörper (N-Term)

Produktnummer ABIN2775636

Produktdetails anti-AMOTL1 Antikörper

Target: AMOTL1 (Angiomotin Like 1 (AMOTL1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AMOTL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LTQEDPQMVY QSARQEPQGQ EHQVDNTVME KQVRSTQPQQ NNEELPTYEE

Homologie: Cow: 93%, Dog: 79%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against AMOTL1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AMOTL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 956 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-AMOTL1 Antikörper (ABIN2775636)

Skouloudaki, Walz: "YAP1 recruits c-Abl to protect angiomotin-like 1 from Nedd4-mediated degradation." in: PLoS ONE, Vol. 7, Issue 4, pp. e35735, (2012) (PubMed).

Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: "The LIFEdb database in 2006." in: Nucleic acids research, Vol. 34, Issue Database issue, pp. D415-8, (2005) (PubMed).

Details zu AMOTL1

Target: AMOTL1 (Angiomotin Like 1 (AMOTL1))

Andere Bezeichnung: AMOTL1 (AMOTL1 Produkte)

Synonyme: JEAP antikoerper, 2310010G08Rik antikoerper, 2310067L22Rik antikoerper, 4932416D09Rik antikoerper, mFLJ00155 antikoerper, angiomotin like 1 antikoerper, angiomotin-like 1 antikoerper, AMOTL1 antikoerper, Amotl1 antikoerper

Hintergrund: AMOTL1 is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation.
Alias Symbols: JEAP
Protein Interaction Partner: WWOX, SUZ12, NEDD4, HECW2, AMOT, LATS2, YAP1, LATS1, Wwtr1, UBC, Magi1, NEDD4L,
Protein Size: 956

Molekulargewicht: 106 kDa

Gen-ID: 154810

NCBI Accession: NM_130847, NP_570899

UniProt: Q8IY63