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UBE2D3 Antikörper (N-Term)

UBE2D3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2775674
  • Target Alle UBE2D3 Antikörper anzeigen
    UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)
    Wirt
    • 33
    • 1
    Kaninchen
    Klonalität
    • 33
    • 1
    Polyklonal
    Konjugat
    • 13
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UBE2D3 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 20
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    MALKRINKEL SDLARDPPAQ CSAGPVGDDM FHWQATIMGP NDSPYQGGVF
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Yeast: 92%, Zebrafish: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against UBE2D3. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2D3
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 147 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    UBE2D3 (Ubiquitin-Conjugating Enzyme E2D 3 (UBE2D3))
    Andere Bezeichnung
    UBE2D3 (UBE2D3 Produkte)
    Synonyme
    E2(17)KB3 antikoerper, UBC4/5 antikoerper, UBCH5C antikoerper, eff antikoerper, fb36f02 antikoerper, wu:fb36f02 antikoerper, zgc:56340 antikoerper, 1100001F19Rik antikoerper, 9430029A22Rik antikoerper, AA414951 antikoerper, UBE2D3P antikoerper, Xubc4 antikoerper, e2(17)kb3 antikoerper, ubc4/5 antikoerper, ubch5c antikoerper, ube2d3.1 antikoerper, ube2d2 antikoerper, xubc4 antikoerper, wu:fj13d01 antikoerper, zgc:73200 antikoerper, ubiquitin conjugating enzyme E2 D3 antikoerper, ubiquitin-conjugating enzyme E2D 3 antikoerper, ubiquitin conjugating enzyme E2 D3 L homeolog antikoerper, ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), like antikoerper, UBE2D3 antikoerper, ube2d3 antikoerper, Ube2d3 antikoerper, LOC100223566 antikoerper, ube2d3.L antikoerper, ube2d2l antikoerper
    Hintergrund
    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2D3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined.
    Alias Symbols: E2(17)KB3, MGC43926, MGC5416, UBC4/5, UBCH5C
    Protein Interaction Partner: NHLRC1, DTX2, TRIM63, RNF146, RNF26, RBX1, UBC, RNF5, RNF2, NEDD4, MID1, STUB1, TRIM39, OTUB1, MDM2, RNF111, TRIM33, PRPF19, RNF115, TRIM58, BTRC, MARCH7, NFKBIA, ARIH1, FBXW11, UBE2D3, PARK2, BRCA1, BARD1, UBE3A, MSL1, UBA1, CBLC, SMURF1, RNF130, UBA6, M
    Protein Size: 147
    Molekulargewicht
    17 kDa
    Gen-ID
    7323
    NCBI Accession
    NM_003340, NP_003331
    UniProt
    P61077
    Pathways
    Activation of Innate immune Response, Toll-Like Receptors Cascades
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