UBE2E1 Antikörper (Middle Region)

Produktnummer ABIN2775676

Produktdetails anti-UBE2E1 Antikörper

Target: UBE2E1 (Ubiquitin-Conjugating Enzyme E2E 1 (UBE2E1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Kaninchen, Hund, Meerschweinchen, Ratte, Pferd, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2E1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PKGDNIYEWR STILGPPGSV YEGGVFFLDI TFTPEYPFKP PKVTFRTRIY

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against UBE2E1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UBE2E1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 193 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UBE2E1

Target: UBE2E1 (Ubiquitin-Conjugating Enzyme E2E 1 (UBE2E1))

Andere Bezeichnung: UBE2E1 (UBE2E1 Produkte)

Hintergrund: UBE2E1 catalyzes the covalent attachment of ubiquitin to other proteins. UBE2E1 mediates the selective degradation of short-lived and abnormal proteins.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: UBCH6
Protein Interaction Partner: TRIM33, RNF11, TRIM32, UBC, TRAF6, MID1, TRIM23, XIAP, NHLRC1, ZNRF1, JADE1, RNF26, SLX8, SLX5, MARCH7, UBE2E1, MARCH5, RNF167, UBA1, RNF130, USP7, NEDD4, Rag1, ZNF827, PARK2, BRCA1, RNF122, RNF128, ITCH, TRIM39, RNF20, FBXO2, WWP2, STUB1, TOPORS, TRIM28,
Protein Size: 193

Molekulargewicht: 21 kDa

Gen-ID: 7324

NCBI Accession: NM_003341, NP_003332

UniProt: P51965

Pathways: Ubiquitin Proteasome Pathway