UBE2M Antikörper (N-Term)

Produktnummer ABIN2775686

Produktdetails anti-UBE2M Antikörper

Target: UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2M Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: IKLFSLKQQK KEEESAGGTK GSSKKASAAQ LRIQKDINEL NLPKTCDISF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against UBE2M. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human UBE2M

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 183 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-UBE2M Antikörper (ABIN2775686)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Details zu UBE2M

Target: UBE2M (ube2m) (Ubiquitin-Conjugating Enzyme E2M (ube2m))

Andere Bezeichnung: UBE2M (ube2m Produkte)

Synonyme: DDBDRAFT_0204633 antikoerper, DDBDRAFT_0238042 antikoerper, DDB_0204633 antikoerper, DDB_0238042 antikoerper, UBC-RS2 antikoerper, UBC12 antikoerper, hUbc12 antikoerper, 2510040H03Rik antikoerper, Ubc-rs2 antikoerper, ubiquitin conjugating enzyme E2M antikoerper, ubiquitin-conjugating enzyme E2M antikoerper, ubiquitin conjugating enzyme E2 M antikoerper, NEDD8-conjugating enzyme antikoerper, ubiquitin conjugating enzyme E2M S homeolog antikoerper, ube2m antikoerper, LOC692934 antikoerper, UBE2M antikoerper, Ube2m antikoerper, ube2m.S antikoerper

Hintergrund: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2M is a member of the E2 ubiquitin-conjugating enzyme family. It is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin.
Alias Symbols: UBC-RS2, UBC12, hUbc12
Protein Interaction Partner: DCUN1D1, DCUN1D4, RBX1, UBC, MARCH7, UBE2M, CUL1, DCUN1D3, SMURF1, CAND1, DCUN1D2, NEDD8, DCUN1D5, LMNA, VCAM1, ITGA4, FN1, VCP, UBE2D2, TYMS, TST, VAMP2, PARK2, PINK1, UBE2T, SEC22B, SLC9A3R2, APP, CUL3, CUL4A, TP53, UBD, COPS6, UBA3, NAE1, CUL2, Nedd4,
Protein Size: 183

Molekulargewicht: 21 kDa

Gen-ID: 9040

NCBI Accession: NM_003969, NP_003960

UniProt: P61081